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[红细胞中PGM1的酶活性]

[Enzyme activity of PGM1 in erythrocytes].

作者信息

Bajanowski T, Baumann A, Brinkmann B

机构信息

Institut für Rechtsmedizin, Westfälische Wilhelms-Universität, Münster, Bundesrepublik Deutschland.

出版信息

Z Rechtsmed. 1990;103(8):609-12. doi: 10.1007/BF01261426.

Abstract

The enzyme activity of phosphoglucomutase (PGM) has been investigated in red cell haemolysates from 142 individuals and compared to the sub-type as determined by isoelectric focusing. The 10 phenotypes showed significant differences in PGM-activity which indicates that there is a correlation between the level of activity and the isolelectric point of homozygotes. No indication of silent alleles or alleles with reduced activity was found in this collective.

摘要

对142名个体的红细胞溶血产物中的磷酸葡萄糖变位酶(PGM)的酶活性进行了研究,并与通过等电聚焦确定的亚型进行了比较。这10种表型在PGM活性上表现出显著差异,这表明纯合子的活性水平与等电点之间存在相关性。在这个群体中未发现沉默等位基因或活性降低的等位基因的迹象。

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