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Development of tolerance to the ACTH-releasing effects of beta-endorphin.

作者信息

Van Loon G R, De Souza E B

出版信息

Res Commun Chem Pathol Pharmacol. 1978 Oct;22(1):203-4.

PMID:214831
Abstract

Acute intracisternal injection of human beta-endorphin results in increased plasma concentration of adrenocorticotropic hormone (ACTH). Repeated injections of beta-endorphin are associated with the development of tolerance with regard to this ACTH-stimulating effect.

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