Department of Neurology, Istanbul University, Istanbul Medical School, Edip Aktin Stroke Unit, Capa, Istanbul, Turkey.
Neurol India. 2011 Mar-Apr;59(2):174-9. doi: 10.4103/0028-3886.79130.
We aimed to investigate gender differences in Turkish stroke patients.
Demographics, risk factors, clinical and etiologic subtypes, laboratory findings, clinical course, and in-hospital prognosis of 1 522 patients with ischemic stroke (IS) and 320 patients with intracerebral hemorrhage prospectively registered in the Istanbul Medical School Stroke Registry (1994-2004) were analyzed separately.
The mean age of IS patients was higher in females (n : 751) (P<0.0001). In males, smoking, ischemic heart disease, peripheral arterial disease, posterior circulation syndromes, and strokes due to large-artery atherosclerosis were more common (P<0.0001 for each). Prestroke disability, atrial fibrillation (P<0.0001), hypertension (P=0.041), modified Rankin Scale (mRS) 3-5 at admission (P<0.0001), total anterior circulation syndrome (P<0.0001), and cardioembolic stroke (P<0.0001) were more frequent in females. Female gender was an independent predictor of poor outcome (mRS 3-6).
Gender differences were observed exclusively in patients with IS. Although our patients were younger than those reported, gender differences were similar.
我们旨在研究土耳其脑卒中患者的性别差异。
对 1522 例缺血性脑卒中（IS）患者和 320 例颅内出血患者的人口统计学、危险因素、临床和病因亚型、实验室检查结果、临床病程和住院预后进行了前瞻性登记，并分别对其进行了分析。这些患者均来自伊斯坦布尔医学院脑卒中登记处（1994-2004 年）。
女性（n=751）IS 患者的平均年龄较高（P<0.0001）。在男性中，吸烟、缺血性心脏病、外周动脉疾病、后循环综合征和大动脉粥样硬化性脑卒中更为常见（P<0.0001）。女性患者在发病前残疾（P<0.0001）、心房颤动（P<0.0001）、高血压（P=0.041）、入院时改良 Rankin 量表（mRS）评分 3-5（P<0.0001）、全前循环综合征（P<0.0001）和心源性脑栓塞（P<0.0001）的发生率更高。女性性别是预后不良（mRS 3-6）的独立预测因素。
仅在 IS 患者中观察到性别差异。尽管我们的患者比报告的患者年轻，但性别差异相似。
