Department of Pathology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Neurol India. 2011 Mar-Apr;59(2):208-11. doi: 10.4103/0028-3886.79142.
Till date there is no published multi-institutional data regarding the epidemiological profile of pediatric brain tumors in India.
The present retrospective study analyses the histological spectrum of pediatric age group brain tumors in seven tertiary care hospitals in India.
Data regarding frequencies of various primary brain tumors (diagnosed according to the World Health Organization (WHO) classification), in 3936 pediatric patients (<18 yrs of age), was collected from seven tertiary care hospitals in India.
The most common primary pediatric brain tumors were astrocytic tumors (34.7%), followed by medulloblastoma and supratentorial primitive neuro-ectodermal tumors (22.4%), craniopharyngiomas (10.2%) and ependymal tumors (9.8%). The most common astrocytic tumor was pilocytic astrocytoma. In comparison to adults, oligodendrogliomas and lymphomas were rare in children.
Our study is the first such report on the histological spectrum of brain tumors in children in India. Except for a slightly higher frequency of craniopharyngiomas, the histological profile of pediatric brain tumors in India is similar to that reported in the Western literature.
目前尚无关于印度儿科脑肿瘤的多机构流行病学数据发表。
本回顾性研究分析了印度七家三级护理医院儿科脑肿瘤的组织学谱。
从印度的七家三级护理医院收集了 3936 名儿科患者（<18 岁）的各种原发性脑肿瘤（根据世界卫生组织（WHO）分类诊断）的频率数据。
最常见的原发性儿科脑肿瘤是星形细胞瘤（34.7%），其次是髓母细胞瘤和幕上原始神经外胚层肿瘤（22.4%）、颅咽管瘤（10.2%）和室管膜瘤（9.8%）。最常见的星形细胞瘤是毛细胞型星形细胞瘤。与成人相比，少突胶质细胞瘤和淋巴瘤在儿童中较为罕见。
我们的研究是印度儿童脑肿瘤组织学谱的首次此类报告。除颅咽管瘤的频率略高外，印度儿科脑肿瘤的组织学特征与西方文献报道的相似。
