Nayil Khursheed, Makhdoomi Rumana, Ramzan Altaf, Zahoor Sheikh, Rasool Mohsin, Wani Abrar, Dhar Anil, Mubeen Basharat, Singh Sarbjit, Bhat Rashid, Kirmani Altaf
Department of Neurosurgery, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India.
Pediatr Neurosurg. 2011;47(1):31-7. doi: 10.1159/000327143. Epub 2011 May 5.
Brain tumors in children represent the second most frequent tumors in this age group after hematologic malignancies. We highlight the demographic pattern after retrospective analysis of brain tumors in children from geographically and ethnically distinct Kashmir Valley managed in our center between 2000 and 2009. We had a total of 248 pediatric patients with brain tumors. The parameters analyzed were age, gender, location of tumors and histopathological subtypes as well as WHO grade of tumor. We also did a comparison between the frequencies of common varieties of tumor in the first and second 5-year periods. We found that 111 tumors (44.75%) were supratentorial, and 137 (55.25%) were infratentorial. The male-to-female ratio was 1.4:1. The proportions of low-grade and high-grade tumors were 60 and 40%, respectively. The most common tumor in our series was astrocytoma. The most common tumors in the supratentorial and infratentorial compartments were craniopharyngioma and medulloblastoma, respectively. Our experience reflects a different demographic profile of pediatric brain tumors as compared with other regions of the world.
儿童脑肿瘤是该年龄组继血液系统恶性肿瘤之后第二常见的肿瘤。通过对2000年至2009年期间在我们中心接受治疗的来自地理和种族不同的克什米尔山谷的儿童脑肿瘤进行回顾性分析，我们突出了其人口统计学模式。我们共有248例患有脑肿瘤的儿科患者。分析的参数包括年龄、性别、肿瘤位置、组织病理学亚型以及肿瘤的WHO分级。我们还对前5年和后5年常见肿瘤类型的发生率进行了比较。我们发现，111例肿瘤（44.75%）位于幕上，137例（55.25%）位于幕下。男女比例为1.4:1。低级别和高级别肿瘤的比例分别为60%和40%。我们系列中最常见的肿瘤是星形细胞瘤。幕上和幕下最常见的肿瘤分别是颅咽管瘤和髓母细胞瘤。我们的经验反映出与世界其他地区相比，儿童脑肿瘤的人口统计学特征有所不同。
