Bremen Institute for Prevention Research and Social Medicine, University Bremen, Germany.
Int J Obes (Lond). 2011 Apr;35 Suppl 1:S3-15. doi: 10.1038/ijo.2011.30.
The European IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children and infants) study was set up to determine the aetiology of overweight, obesity and related disorders in children, and to develop and evaluate a tailored primary prevention programme.
This paper focuses on the aetiological element of the multicentre study, the measures and examinations, sociodemographic characteristics of the study sample and proportions of participation.
Prospective cohort study with an embedded intervention study that started with a baseline survey in eight countries in 2007-2008.
Baseline participants of the prospective cohort study were 16,224 children aged 2-9 years. Parents reported sociodemographic, behavioural, medical, nutritional and other lifestyle data for their children and families. Examinations of children included anthropometry, blood pressure, fitness, accelerometry, DNA from saliva and physiological markers in blood and urine. The built environment, sensory taste perception and other mechanisms of children's food choices and consumer behaviour were studied in subgroups.
Between 1507 and 2567, children with a mean age of 6.0 years and an even sex distribution were recruited from each country. Of them, 82% lived in two-parent families. The distribution of standardised income levels differed by study sample, with low-income groups being strongly represented in Cyprus, Italy and Germany. At least one 24-h dietary recall was obtained for two-thirds of the children. Blood pressure and anthropometry were assessed in more than 90%. A 3-day accelerometry was performed in 46%, motor fitness was assessed in 41%, cardiorespiratory fitness in 35% and ∼11% participated in taste perception tests. The proportion of children donating venous blood, urine and saliva was 57, 86 and 88%, respectively.
The IDEFICS cohort provides valuable data to investigate the interplay of social, environmental, genetic, physiological and behavioural factors in the development of major diet- and lifestyle-related disorders affecting children at present.
欧洲 IDEFICS（儿童和婴儿饮食和生活方式引起的健康影响的识别和预防）研究旨在确定儿童超重、肥胖和相关疾病的病因，并制定和评估有针对性的初级预防计划。
本文重点介绍了这项多中心研究的病因学部分、测量和检查、研究样本的社会人口学特征以及参与率。
前瞻性队列研究，嵌入一项干预研究，该研究于 2007-2008 年在八个国家开始进行基线调查。
前瞻性队列研究的基线参与者为 16224 名 2-9 岁的儿童。父母为其子女和家庭报告社会人口学、行为、医疗、营养和其他生活方式数据。对儿童的检查包括人体测量学、血压、体能、加速度计、唾液中的 DNA 和血液和尿液中的生理标志物。还在亚组中研究了儿童食物选择和消费行为的构建环境、感官味觉感知和其他机制。
在每个国家，平均年龄为 6.0 岁且性别分布均匀的儿童中，有 1507-2567 名儿童被招募。其中，82%的儿童生活在双亲家庭中。研究样本的标准化收入水平分布不同，低收人群体在塞浦路斯、意大利和德国的代表性很强。三分之二的儿童至少进行了一次 24 小时膳食回忆。超过 90%的儿童测量了血压和人体测量学指标。46%的儿童进行了 3 天的加速度计测量，41%的儿童进行了运动体能评估，35%的儿童进行了心肺功能评估，约 11%的儿童参加了味觉感知测试。捐献静脉血、尿液和唾液的儿童比例分别为 57%、86%和 88%。
IDEFICS 队列提供了有价值的数据，可用于研究当前影响儿童的主要饮食和生活方式相关疾病的社会、环境、遗传、生理和行为因素之间的相互作用。
