Aufricht C, Tenner W, Kohlhauser C
Univ.-Kinderklinik Wien.
Klin Padiatr. 1990 Nov-Dec;202(6):396-8. doi: 10.1055/s-2007-1025553.
Lyme borreliosis is currently suspected to be capable of mimicking nearly all known neurologic symptoms and disease entities. The goal of our study is to define the associated anamnestic, clinical and laboratory findings in aseptic meningitis and Lyme borreliosis in childhood by a meta-analysis of recent literature and of our own data. We defined by means of 63 cases derived of 10 publications and own data a list of mainly rather unspecific parameters like insidious onset, fever, mild meningism, encephalitic symptoms and cranial nerve involvement. Mere neurologic presentation without ECM, arthritis or even an anamnestic insect-bite seems to be most frequent. Retrospective studies, however, can not sufficiently characterize the clinical picture of aseptic meningitis in Lyme borreliosis.
目前怀疑莱姆病螺旋体病能够模拟几乎所有已知的神经系统症状和疾病实体。我们研究的目的是通过对近期文献和我们自己的数据进行荟萃分析,来确定儿童无菌性脑膜炎和莱姆病螺旋体病相关的既往史、临床及实验室检查结果。我们通过10篇出版物及自身数据中的63个病例,确定了一系列主要为非特异性的参数,如隐匿起病、发热、轻度脑膜刺激征、脑病症状及脑神经受累。仅表现为神经系统症状,而无游走性红斑、关节炎,甚至没有既往虫咬史的情况似乎最为常见。然而,回顾性研究不足以充分描述莱姆病螺旋体病无菌性脑膜炎的临床表现。