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直线吻合器在预防吻合口狭窄方面比手工缝合或圆形吻合器更有效:一项对照临床研究。

Linear stapled esophagogastrostomy is more effective than hand-sewn or circular stapler in prevention of anastomotic stricture: a comparative clinical study.

机构信息

Department of Thoracic Surgery, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan, 610041, China.

出版信息

J Gastrointest Surg. 2011 Jun;15(6):915-21. doi: 10.1007/s11605-011-1490-1. Epub 2011 Apr 12.

Abstract

OBJECTIVE

The aim of this study was to retrospectively compare the operative effects of linear stapled intrathoracic esophagogastrostomy with hand-sewn or circular stapled anastomosis in prevention of anastomotic stricture.

METHOD

Between October 2007 and October 2009, 293 patients with esophageal or gastric cardia cancer underwent a curative intent resection. Patients received either a linear stapled (LS group, n = 166), conventional hand-sewn (HS group, n = 59), or circular stapled intrathoracic esophagogastric anastomosis (CS group, n = 68). The patients were followed-up and compared at 3 months after the operation.

RESULT

Three groups of patients were comparable on clinical baseline characteristics. There was one operative death in the HS group. The operative complications were documented in 15 patients (5.1%), with no difference among three groups (χ(2) = 2.215, P = 0.330). The follow-up rate was 96.9%. The anastomotic diameter was 1.6 ± 0.4 cm in the LS group, 1.2 ± 0.3 cm in the HS group, and 1.0 ± 0.4 cm in the CS group, respectively (F = 58.110, P < 0.001). The anastomotic stricture rates were 1.9% (3/162) in the LS group, 9.3% (5/54) in the HS group, and 20.9% (14/67) in the CS group, respectively (χ(2) = 24.095, P < 0.001). The reflux score in LS group was lower than other two groups (H = 6.995, P = 0.030).

CONCLUSION

The linear stapled esophagogastrostomy could decrease anastomotic stricture without increasing gastroesophageal reflux.

摘要

目的

本研究旨在回顾性比较直线型吻合器与手工或圆形吻合器行胸内食管胃吻合术在预防吻合口狭窄方面的手术效果。

方法

2007 年 10 月至 2009 年 10 月,293 例食管或胃贲门癌患者接受根治性切除术。患者接受直线型吻合器(LS 组,n=166)、传统手工吻合(HS 组,n=59)或圆形吻合器胸内食管胃吻合术(CS 组,n=68)。术后 3 个月对患者进行随访和比较。

结果

三组患者的临床基线特征具有可比性。HS 组有 1 例手术死亡。15 例(5.1%)患者发生手术并发症,三组之间无差异(χ²=2.215,P=0.330)。随访率为 96.9%。LS 组吻合口直径为 1.6±0.4cm,HS 组为 1.2±0.3cm,CS 组为 1.0±0.4cm(F=58.110,P<0.001)。LS 组吻合口狭窄率为 1.9%(3/162),HS 组为 9.3%(5/54),CS 组为 20.9%(14/67),差异有统计学意义(χ²=24.095,P<0.001)。LS 组反流评分低于其他两组(H=6.995,P=0.030)。

结论

直线型吻合器吻合可降低吻合口狭窄发生率,同时减少胃食管反流。

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