Rytik P G, van der Groen G, Eremin V F, Kolomiets N D, Popov S A, Nijs P, Willems V, Verkauteren G, Il'kevich Iu G, Lemeshko N N
Vopr Virusol. 1990 Sep-Oct;35(5):389-90.
Biological properties of an AIDS agent first isolated from a native citizen in the USSR are presented. The source of the virus was a young Byelorussian woman who in the near past had had sexual contacts with a citizen from one of the Central Africa countries. The isolate is thought to be of HIV-I type. It replicated perfectly in many continuous lymphocyte lines and had HIV-characteristic morphology. The protein spectrum of the isolate was gp120, gp41, p65/51, p55, p32, p24, p17. Reverse transcriptase activity was detected in the culture fluid of the virus-containing cell cultures. The isolate was designated HIV-IZ.
介绍了首次从苏联一名本国公民身上分离出的一种艾滋病病原体的生物学特性。病毒来源是一名年轻的白俄罗斯女性,她近期与一名来自中非国家的公民有过性接触。该分离株被认为是HIV-I型。它能在许多连续淋巴细胞系中完美复制,并具有HIV特征性形态。该分离株的蛋白谱为gp120、gp41、p65/51、p55、p32、p24、p17。在含病毒细胞培养物的培养液中检测到逆转录酶活性。该分离株被命名为HIV-IZ。