Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109-5622, USA.
Am J Hum Biol. 2011 May-Jun;23(3):325-32. doi: 10.1002/ajhb.21134. Epub 2010 Dec 22.
The Mountain Ok (Mt Ok) people of Telefomin, who live at the interior of Papua New Guinea (PNG), were documented over 25 years ago to be one of the shortest populations on record, with average adult height below the fifth percentile (US). Serum Growth Hormone was detectable, Insulin-like Growth Factor-1 and serum indicators of protein nutritional status fell within the normal range, suggesting that these were not primary factors for their relative short stature.
Since the Telefolmin people have experienced recent socioeconomic changes, they were re-evaluated in 2008, to examine height, weight, and body mass index (BMI), for insight into relative contributions of environment and other factors that modulate stature in children and adults.
Cross-sectional anthropometric data were collected from 474 individuals at Telefomin in 2008, and compared with anthropometric data from 342 individuals measured in 1983.
The height of Telefolmin subjects, below the fifth percentile in 1983, remained below the fifth percentile in 2008. Weight and BMI of peripubertal and adult age groups increased from 1983 to 2008. Male and female heights at peripubertal ages were significantly greater in 2008. Nevertheless, final adult height did not change significantly over the 25 years.
Recent socioeconomic changes appear to contribute to increased weight, BMI, and stature at younger ages in the Mt Ok at Telefomin. In contrast, unchanging adult stature may reflect a delay in the impact of socioeconomic changes, or genetic influences that modulate responsiveness to other growth regulators.
生活在巴布亚新几内亚（PNG）内地特罗菲姆的芒特奥克（Mt Ok）人，早在 25 年前就被记录为记录中最短的人群之一，成年人的平均身高低于第五百分位（美国）。可检测到血清生长激素，胰岛素样生长因子-1 和血清蛋白质营养状况指标均在正常范围内，这表明这些不是导致他们相对矮小的主要因素。
由于特罗菲姆人经历了最近的社会经济变化，因此在 2008 年对他们进行了重新评估，以检查身高、体重和体重指数（BMI），以了解环境和其他调节儿童和成人身高的因素的相对贡献。
2008 年从特罗菲姆的 474 个人中收集了横断面人体测量数据，并与 1983 年测量的 342 个人的人体测量数据进行了比较。
特罗菲姆人（1983 年低于第五百分位）的身高在 2008 年仍低于第五百分位。青春期前和成年年龄组的体重和 BMI 从 1983 年到 2008 年增加。青春期前男性和女性的身高在 2008 年显著增加。尽管如此，25 年来成年人的最终身高并没有明显变化。
最近的社会经济变化似乎导致芒特奥克在特罗菲姆的年轻人中体重、BMI 和身高增加。相比之下，成年人身高不变可能反映了社会经济变化影响的延迟，或调节对其他生长调节剂反应性的遗传影响。
