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循证牙科

Evidence-based dentistry.

作者信息

Chambers David W

出版信息

J Am Coll Dent. 2010 Winter;77(4):68-80.

Abstract

Both panegyric and criticism of evidence-based dentistry tend to be clumsy because the concept is poorly defined. This analysis identifies several contributions to the profession that have been made under the EBD banner. Although the concept of clinicians integrating clinical epidemiology, the wisdom of their practices, and patients' values is powerful, its implementation has been distorted by a too heavy emphasis of computerized searches for research findings that meet the standards of academics. Although EBD advocates enjoy sharing anecdotal accounts of mistakes others have made, faulting others is not proof that one's own position is correct. There is no systematic, high-quality evidence that EBD is effective. The metaphor of a three-legged stool (evidence, experience, values, and integration) is used as an organizing principle. "Best evidence" has become a preoccupation among EBD enthusiasts. That overlong but thinly developed leg of the stool is critiqued from the perspectives of the criteria for evidence, the difference between internal and external validity, the relationship between evidence and decision making, the ambiguous meaning of "best," and the role of reasonable doubt. The strongest leg of the stool is clinical experience. Although bias exists in all observations (including searches for evidence), there are simple procedures that can be employed in practice to increase useful and objective evidence there, and there are dangers in delegating policy regarding allowable treatments to external groups. Patient and practitioner values are the shortest leg of the stool. As they are so little recognized, their integration in EBD is problematic and ethical tensions exist where paternalism privileges science over patient's self-determined best interests. Four potential approaches to integration are suggested, recognizing that there is virtually no literature on how the "seat" of the three-legged stool works or should work. It is likely that most dentists choose to wait for collective professional standards to reveal acceptable practice or follow a strategy of punctuated equilibrium, only switching out established practice habits when very conspicuous advantages are identified. Integration in medicine appears to follow the statistically sophisticated practice of updating estimates of clinical parameters (probabilities) for diagnoses, treatments, prognoses, and side-effects. This approach is likely beyond the skill or interest of clinical dentists and it fails to incorporate values in the integration. The use of decision trees to integrate both research and experiential parameters and values is illustrated and it is shown that such a technique identifies why there are very few cases in dentistry where evidence needs to be consulted and indicates what such cases are.

摘要

对循证牙科的赞扬和批评往往都不得要领,因为这一概念的定义很模糊。本分析确定了在循证牙科旗帜下对该专业所做的一些贡献。尽管临床医生将临床流行病学、实践经验和患者价值观相结合的理念很有影响力,但其实施却因过于强调通过计算机搜索符合学术标准的研究结果而被扭曲。尽管循证牙科的支持者喜欢分享他人所犯错误的轶事,但指责他人并不能证明自己的立场是正确的。没有系统的、高质量的证据表明循证牙科是有效的。用三条腿的凳子(证据、经验、价值观和整合)作比喻作为一种组织原则。“最佳证据”已成为循证牙科支持者关注的焦点。从证据标准、内部效度与外部效度的差异、证据与决策的关系、“最佳”的模糊含义以及合理怀疑的作用等角度,对凳子那条过长但阐述薄弱的腿进行了批判。凳子最强壮的腿是临床经验。尽管所有观察(包括证据搜索)都存在偏差,但在实践中可以采用一些简单程序来增加有用和客观的证据,而且将可允许治疗的政策委托给外部团体存在风险。患者和从业者的价值观是凳子最短的腿。由于它们很少得到认可,它们在循证牙科中的整合存在问题,并且当家长式作风将科学置于患者自主决定的最大利益之上时,就会出现伦理紧张关系。提出了四种潜在的整合方法,同时认识到几乎没有关于三条腿凳子的“座位”如何运作或应该如何运作的文献。很可能大多数牙医选择等待集体专业标准揭示可接受的做法,或者遵循间断平衡策略,只有在发现非常明显的优势时才改变既定的实践习惯。医学中的整合似乎遵循统计上复杂的做法,即更新诊断、治疗、预后和副作用的临床参数(概率)估计。这种方法可能超出了临床牙医的技能或兴趣范围,而且它没有在整合中纳入价值观。文中举例说明了使用决策树来整合研究参数、经验参数和价值观,并表明这种技术可以确定为什么牙科中几乎没有需要参考证据的病例,并指出是哪些病例。

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