Bernard J F, Renoux M, Dhermy D, Schneider M, Chouraqui F, Amar M, Boivin P
Sem Hop. 1978;54(25-28):797-804.
The authors report the clinical and hematological course of 20 patients with polycythemia vera complicated by acute leukemia. This was responsible for 35,8% of the 53 deaths in the series of 103 patients treated with radioactive phosphorus. It occurred on average 12 years after the first treatment. The data in these cases are compared with those in the literature. The role of ionising radiation and/or the myelo-proliferative syndrome itself in the onset of acute leukemia is discussed.
作者报告了20例真性红细胞增多症并发急性白血病患者的临床和血液学病程。在接受放射性磷治疗的103例患者系列中,这是53例死亡病例中35.8%的死因。它平均在首次治疗后12年发生。将这些病例的数据与文献中的数据进行了比较。讨论了电离辐射和/或骨髓增殖综合征本身在急性白血病发病中的作用。