Check J H, Katsoff B, Brasile D, Wilson C, Summers-Chase D
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, NJ, USA.
Clin Exp Obstet Gynecol. 2011;38(1):26-7.
To determine any differences in pregnancy rates if frozen-thawed embryos are transferred to a gestational carrier if the source of oocytes came from infertile women trying to conceive vs a paid egg donor.
Gestational carriers were used because of uterine problems or health issues. If there was adequate ovarian egg reserve, controlled ovarian hyperstimulation followed by oocyte retrieval was performed on the infertile woman. Otherwise an egg donor was used.
No differences in clinical and ongoing delivered pregnancy rates were found but a trend for higher implantation rates in the paid donors was evident.
The trend for higher implantation rates when a paid donor was the source of oocytes may be age-related (35.9 for infertile women vs 29.5 for paid donors). The pregnancy results with frozen embryos were sufficient to allow women to proceed with oocyte retrieval if time is of the essence even if a gestational carrier has not as yet been found.
确定如果冻融胚胎被移植到代孕载体中，当卵母细胞来源为试图受孕的不孕妇女与有偿卵子捐赠者时，妊娠率是否存在差异。
因子宫问题或健康问题使用代孕载体。如果有足够的卵巢卵子储备，则对不孕妇女进行控制性卵巢过度刺激，随后进行卵母细胞采集。否则使用卵子捐赠者。
未发现临床妊娠率和持续分娩妊娠率存在差异，但有偿捐赠者的着床率有升高趋势明显。
当有偿捐赠者为卵母细胞来源时着床率较高的趋势可能与年龄有关（不孕妇女为35.9岁，有偿捐赠者为29.5岁）。如果时间至关重要，即使尚未找到代孕载体，冻融胚胎的妊娠结果也足以让女性进行卵母细胞采集。
