Check J H, Cohen R
The University of Medicine and Dentistry of New Jersey, Camden, NJ, USA.
Clin Exp Obstet Gynecol. 2011;38(1):88-9.
To determine if relief from various pain conditions with sympathomimetic amines may be a direct effect on pain fibers or related to improvement of edema.
A woman with severe migraine headaches resistant to standard therapy was treated with dextroamphetamine sulfate.
The headaches markedly improved shortly after treatment as did her vasomotor symptoms. However, in this case the inability to lose weight despite dieting related to edema did not improve.
The improvement of pain and vasomotor symptoms in this disorder of the sympathetic nervous system does not seem to necessarily be related to edema causing pain. Sympathomimetic amines may have a direct effect on sympathetic nervous system fibers. Thus, a more appropriate term for this condition instead of idiopathic orthostatic cyclic edema would be sympathetic hyperalgesia-edema syndrome.
确定拟交感神经胺缓解各种疼痛状况是对痛觉纤维的直接作用还是与水肿改善有关。
一名对标准治疗有抵抗的重度偏头痛女性患者接受硫酸右旋苯丙胺治疗。
治疗后不久头痛明显改善,其血管舒缩症状也如此。然而,在这种情况下,尽管节食但与水肿相关的体重无法减轻并未改善。
在这种交感神经系统疾病中,疼痛和血管舒缩症状的改善似乎不一定与水肿引起的疼痛有关。拟交感神经胺可能对交感神经系统纤维有直接作用。因此,对于这种情况,比起特发性直立性周期性水肿,更合适的术语是交感神经性痛觉过敏-水肿综合征。