有证据表明，女性偏头痛可能与交感神经系统的一种常见缺陷有关，拟交感神经胺治疗后症状明显改善即为证明。
Evidence that migraine headaches in women may be related to a common defect in the sympathetic nervous system as evidenced by marked improvement following treatment with sympathomimetic amines.
作者信息
Check J H, Cohen R, Check D
机构信息
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA.
出版信息
Clin Exp Obstet Gynecol. 2011;38(2):180-1.
PURPOSE
To describe a novel therapy for women with intractable migraine headaches.
METHODS
Dextroamphetamine sulfate was prescribed to a 33-year-old woman with intractable migraine headaches resistant to standard therapy. Her only abnormality noted was unexplained weight gain. She failed a water load test.
RESULTS
The headaches were 100% relieved by dextroamphetamine sulfate (Spansule - 45 mg/day).
CONCLUSIONS
Intractable migraine headaches can be added to the list of various pain syndromes related to a disorder of the sympathetic nervous system resistant to standard therapy but showing dramatic improvement with treatment with sympathomimetic amines.
目的
描述一种针对患有顽固性偏头痛的女性的新型疗法。
方法
给一名33岁患有顽固性偏头痛且对标准疗法耐药的女性开了硫酸右旋苯丙胺。唯一发现的异常是不明原因的体重增加。她水负荷试验未通过。
结果
硫酸右旋苯丙胺（长效胶囊 - 45毫克/天）使头痛得到了100%缓解。
结论
顽固性偏头痛可被列入与交感神经系统紊乱相关的各种疼痛综合征名单，这些综合征对标准疗法耐药，但使用拟交感神经胺治疗后有显著改善。
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