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抑郁症的激素治疗

Hormone treatment of depression.

作者信息

Joffe Russell T

机构信息

LIJ North Shore Staten Island University Hospital, New York 10305, USA.

出版信息

Dialogues Clin Neurosci. 2011;13(1):127-38. doi: 10.31887/DCNS.2011.13.1/rjoffe.

DOI:10.31887/DCNS.2011.13.1/rjoffe
PMID:21485752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3181966/
Abstract

There is a well-established relationship between alterations of various hormonal systems and psychiatric disorders, both in endocrine and psychiatric patients. This has led to clinical and research studies examining the efficacy of the different hormones for treatment of depression. These data will be reviewed with particular regard to the thyroid, gonadal, pineal, and adrenal cortex hormones. The data generally provide limited, but varying evidence for the antidepressant efficacy of these hormones.

摘要

在内分泌患者和精神科患者中,各种激素系统的改变与精神障碍之间存在着已被充分证实的关系。这引发了临床和研究性试验,以检验不同激素治疗抑郁症的疗效。将特别针对甲状腺、性腺、松果体和肾上腺皮质激素对这些数据进行综述。这些数据总体上为这些激素的抗抑郁疗效提供了有限但各不相同的证据。

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A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression).一项针对性腺功能减退且患有阈下抑郁(心境恶劣或轻度抑郁)的老年男性进行睾酮治疗的随机、双盲、安慰剂对照研究。
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