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单纯腹腔镜与开放活体供肾肾切除术:健康调查与移植肾功能评估

Pure laparoscopic versus open live donor nephrectomy: evaluation of health survey and graft functions.

作者信息

Genc V, Ozgencil E, Orozakunov E, Can O S, Yilmaz A A, Ozsay O, Cipe G, Oztuna D, Cakmak A, Tuzuner A, Hazinedaroglu S M

机构信息

Department of Surgery, Ankara University School of Medicine, Ankara, Turkey.

出版信息

Transplant Proc. 2011 Apr;43(3):791-4. doi: 10.1016/j.transproceed.2011.01.099.

Abstract

BACKGROUND

Laparoscopic donor nephrectomy (LDN) has become the gold standard in many kidney transplantation centers seeking to increase the number of potential live donors. This study was designed to compare the health surveys and graft functions between LDN and open donor nephrectomy (ODN).

METHODS

We retrospectively analyzed all patients who underwent donor nephrectomy between December 2005 and September 2009 who had at least 1 year of follow-up. We reviewed demographic data, operative time, warm ischemia period, graft function, and quality of life.

RESULTS

Among the 132 cases, 98 were pure LDN and 34 were ODN. Demographic data were similar in both groups. Operative times were significantly longer in the ODN group but warm ischemia times significantly longer in the LDN group. However, graft functions were similar in both groups. There was 1 graft loss due to arterial thrombosis of the transplanted kidney among the LDN group. Short-Form 36 health survey scores were similar except for the role-physical subscale.

CONCLUSION

Although we failed to observe a significant difference between ODN and LDN as far as the quality of life and graft functions were concerned, the previously documented advantages of laparoscopy with similar operative results suggest? LDN to be the gold standard for this procedure in our institution.

摘要

背景

在许多旨在增加潜在活体供者数量的肾脏移植中心,腹腔镜供肾切除术(LDN)已成为金标准。本研究旨在比较LDN与开放供肾切除术(ODN)患者的健康调查情况及移植肾功能。

方法

我们回顾性分析了2005年12月至2009年9月期间接受供肾切除术且至少随访1年的所有患者。我们查阅了人口统计学数据、手术时间、热缺血时间、移植肾功能及生活质量。

结果

132例患者中,98例行单纯LDN,34例行ODN。两组人口统计学数据相似。ODN组手术时间显著更长,但LDN组热缺血时间显著更长。然而,两组移植肾功能相似。LDN组中有1例因移植肾动脉血栓形成导致移植肾丢失。除生理功能子量表外,36项简明健康调查评分相似。

结论

尽管就生活质量和移植肾功能而言,我们未能观察到ODN与LDN之间存在显著差异,但先前记录的腹腔镜手术优势及相似的手术结果表明,LDN是我们机构该手术的金标准。

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