通过原位杂交将人α干扰素受体基因定位于21号染色体q22.1区。
Assignment of the human interferon-alpha receptor gene to chromosome 21q22.1 by in situ hybridization.
作者信息
Lutfalla G, Roeckel N, Mogensen K E, Mattei M G, Uzé G
机构信息
Laboratoire d'Oncologie Virale, CNRS UPR 274, Villejuif, France.
出版信息
J Interferon Res. 1990 Oct;10(5):515-7. doi: 10.1089/jir.1990.10.515.
PMID:2148760
Abstract
The human interferon-alpha receptor gene (IFN AR) has been assigned to the long arm of human chromosome 21 (report of the committee on the genetic constitution of chromosomes 20 and 21; Ref 1). The present report confirms the assignment and refines the mapping to the 21q22.1 band, using a cDNA probe for the human IFN AR gene and in situ hybridization to metaphase chromosomes.
摘要
人类α干扰素受体基因（IFN AR）已被定位于人类第21号染色体长臂（染色体20和21基因组成委员会报告；参考文献1）。本报告通过使用人类IFN AR基因的cDNA探针及中期染色体原位杂交技术，证实了这一定位，并将其定位精确至21q22.1带。
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