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儿童结节性多动脉炎和银屑病关节炎共存:一种未报道的关联:结节性多动脉炎和银屑病关节炎。

Coexistence of polyarteritis nodosa and psoriatic arthritis in a child: an unreported association: Polyarteritis nodosa and Psoriatic arthitritis.

机构信息

Department of Pediatrics, Complejo Asistencial Universitario de León, C/Altos de Nava s/n, León, 24008, Spain.

出版信息

Eur J Pediatr. 2011 Sep;170(9):1213-5. doi: 10.1007/s00431-011-1459-9. Epub 2011 Apr 13.

Abstract

Polyarteritis nodosa (PAN) is a non-frequent vasculitis of small- and medium-sized vessels. Psoriatic arthritis (PA) is described as a "unique inflammatory arthritis associated with psoriasis" with an inexact prevalence rate due to the lack of widely accepted classification criteria. We describe the case of an 11-year-old boy that presented with fever of unknown origin plus clinical signs of sacroiliitis, bilateral enthesitis of the plantar fascia, and skin psoriasis. He acutely developed erythematous and tender nodular lesions in the lower limbs that lasted around 3 weeks and spontaneously disappeared at the same time as the fever. He was diagnosed as having PAN and PA according to clinical and histological criteria. This is the first report of the coexistence of PAN and PA in a child indicating a possible relation (maybe cross-reactivity of an infectious agent) between PAN and spondiloarthritis.

摘要

结节性多动脉炎(PAN)是一种不常见的小-中血管血管炎。银屑病关节炎(PA)被描述为一种“与银屑病相关的独特炎症性关节炎”,由于缺乏广泛接受的分类标准,其发病率并不确切。我们描述了一例 11 岁男孩的病例,他表现为不明原因发热,伴有骶髂关节炎的临床体征,双侧足底筋膜附着点炎,以及皮肤银屑病。他急性出现下肢红斑性和触痛性结节性病变,持续约 3 周,与发热同时自发消退。根据临床和组织学标准,他被诊断为 PAN 和 PA。这是首例儿童同时患有 PAN 和 PA 的报告,表明两者之间可能存在关联(可能是感染因子的交叉反应)。

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