Zeuzem S, Olbrich H G, Haak T, Jungmann E
Center of Internal Medicine, University Hospital, Johann Wolfgang Goethe-University, Frankfurt am Main, FRG.
Eur J Clin Pharmacol. 1990;39(1):77-9. doi: 10.1007/BF02657063.
In a double-blind study 8 healthy male subjects received 100 micrograms human atrial natriuretic facotr-(99-126) (hANF) and NaCl0.9% in random order on different days. Following hANF injection a significant increase in cardiac beat-to-beat variation was observed (4.65% vs 5.95%). This shows that in vivo human atrial natriuretic factor stimulates cardiac parasympathetic activity in man.
Zotero 插件