Laboratory of Aquaculture & Artemia Reference Center, Ghent University, Rozier 44, B-9000 Gent, Belgium.
Curr Opin Microbiol. 2011 Jun;14(3):251-8. doi: 10.1016/j.mib.2011.03.004. Epub 2011 Apr 12.
The wide and frequent use of antibiotics in aquaculture has resulted in the development and spread of antibiotic resistance. Because of the health risks associated with the use of antibiotics in animal production, there is a growing awareness that antibiotics should be used with more care. This is reflected in the recent implementation of more strict regulations on the prophylactic use of antibiotics and the presence of antibiotic residues in aquaculture products. For a sustainable further development of the aquaculture industry, novel strategies to control bacterial infections are needed. This review evaluates several alternative biocontrol measures that have emerged recently. Most of these methods are still in research phase; few have been tested in real aquaculture settings. It is important to further develop different strategies that could be combined or used in rotation in order to maximise the chance of successfully protecting the animals and to prevent resistance development.
抗生素在水产养殖中的广泛和频繁使用导致了抗生素耐药性的产生和传播。由于在动物生产中使用抗生素相关的健康风险，人们越来越意识到应该更加谨慎地使用抗生素。这反映在最近对预防性使用抗生素和水产养殖产品中抗生素残留实施了更严格的规定上。为了可持续地进一步发展水产养殖业，需要新的策略来控制细菌感染。本综述评估了最近出现的几种替代生物防治措施。这些方法中的大多数仍处于研究阶段；很少有在实际水产养殖环境中进行测试。重要的是要进一步开发不同的策略，可以将它们组合或轮流使用，以最大程度地成功保护动物并防止耐药性的发展。
