Mohammed Elshafia Ali Hamid, Kovács Béla, Kuunya Ronald, Mustafa Eltayeb Omaima Awad, Abbo Azza Siddig Hussien, Pál Károly
Department of Animal Husbandry, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Animal Science, University of Debrecen, 4032 Debrecen, Hungary.
Antibiotics (Basel). 2025 Jun 11;14(6):598. doi: 10.3390/antibiotics14060598.
Antibiotic resistance in aquaculture has emerged as a global crisis, representing a serious threat to the health of aquatic animals, environment, and human. The extensive use of antibiotics in aquaculture has led to rapid development of resistant bacterial strains, resulting in environmental contamination and the dissemination of resistant genes. Understanding of the research trends, key contributors, and thematic evolution of this field is essential for guiding future studies and policy interventions. The study aimed to conduct a bibliometric analysis of research on antibiotic resistance development in aquaculture, identifying key areas of research, leading contributors, emerging challenges, and alternative solutions. Data were extracted from the Web of Science (WoS) database covering the period from 2000 to 2025. A systematic search strategy was employed, utilizing terms including "antibiotic resistance" AND "bacteria," AND "aquaculture". Relevant publications were extracted from the WoS using these keywords. R-tool was then used to analyze the obtained metadata including keywords, citation patterns, and co-authored country. The analysis revealed a remarkable increase in publications over the past 25 years, with key contributions from China, India, and the USA. The most significant articles focused on the presence of multidrug resistant bacteria in the aquatic environments and, antibiotic-resistant genes, and horizontal gene transfer. Probiotics are the alternative solution to overcome the antibiotic resistance and enhance aquaculture sustainability. Future research should focus on the interdisciplinary collaboration, novel antimicrobial alternatives, and global monitoring approaches.
水产养殖中的抗生素耐药性已成为全球危机，对水生动物健康、环境和人类构成严重威胁。水产养殖中抗生素的广泛使用导致耐药菌株迅速发展，造成环境污染和耐药基因传播。了解该领域的研究趋势、主要贡献者和主题演变对于指导未来研究和政策干预至关重要。该研究旨在对水产养殖中抗生素耐药性发展的研究进行文献计量分析，确定关键研究领域、主要贡献者、新出现的挑战和替代解决方案。数据从涵盖2000年至2025年的科学网（WoS）数据库中提取。采用了系统的搜索策略，使用了包括“抗生素耐药性”、“细菌”和“水产养殖”等术语。使用这些关键词从WoS中提取相关出版物。然后使用R工具分析获得的元数据，包括关键词、引用模式和共同作者国家。分析显示，在过去25年中出版物数量显著增加，中国、印度和美国做出了主要贡献。最重要的文章集中在水生环境中多重耐药细菌的存在、抗生素耐药基因和水平基因转移。益生菌是克服抗生素耐药性和增强水产养殖可持续性的替代解决方案。未来的研究应侧重于跨学科合作、新型抗菌替代品和全球监测方法。
