Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Ste B, San Diego, CA 92123, USA.
Mayo Clin Proc. 2011 May;86(5):427-43. doi: 10.4065/mcp.2010.0392. Epub 2011 Apr 13.
Rhinosinusitis (RS) affects approximately 1 in 7 adults in the United States, and its effect on quality of life, productivity, and finances is substantial. During the past 10 years, several expert panels from authoritative bodies have published evidence-based guidelines for the diagnosis and management of RS and its subtypes, including acute viral RS, acute bacterial RS, chronic RS (CRS) without nasal polyposis, CRS with nasal polyposis, and allergic fungal RS. This review examines and compares the recommendations of the Rhinosinusitis Initiative, the Joint Task Force on Practice Parameters, the Clinical Practice Guideline: Adult Sinusitis, the European Position Paper on Rhinosinusitis and Nasal Polyps 2007, and the British Society for Allergy and Clinical Immunology. Points of consensus and divergent opinions expressed in these guidelines regarding classification, diagnosis, and management of adults with acute RS (ARS) and CRS and their various subtypes are highlighted for the practicing clinician. Key points of agreement regarding therapy in the guidelines for ARS include the efficacy of symptomatic treatment, such as intranasal corticosteroids, and the importance of reducing the unnecessary use of antibiotics in ARS; however, guidelines do not agree precisely regarding when antibiotics should be considered as a reasonable treatment strategy. Although the guidelines diverge markedly on the management of CRS, the diagnostic utility of nasal airway examination is acknowledged by all. Important and relevant data from MEDLINE-indexed articles published since the most recent guidelines were issued are also considered, and needs for future research are discussed.
鼻窦炎(RS)影响了大约美国每 7 个成年人中的 1 个,它对生活质量、生产力和财务状况的影响是巨大的。在过去的 10 年中,来自权威机构的几个专家小组发布了基于证据的 RS 及其亚型(包括急性病毒性 RS、急性细菌性 RS、无鼻息肉的慢性 RS(CRS)、有鼻息肉的 CRS 和变应性真菌性 RS)的诊断和管理指南。这篇综述考察并比较了鼻科炎症倡议、联合实践参数工作组、成人鼻窦炎临床实践指南、2007 年欧洲鼻-鼻窦炎和鼻息肉立场文件以及英国变态反应和临床免疫学学会的建议。对于临床医生来说,这些指南中关于急性 RS(ARS)和 CRS 及其各种亚型的分类、诊断和管理的共识和不同意见的要点被突出显示。在 ARS 指南中,关于治疗的主要共识包括对症治疗(如鼻腔皮质类固醇)的疗效,以及减少 ARS 中不必要使用抗生素的重要性;然而,指南在何时应考虑抗生素作为合理治疗策略方面并没有完全达成一致。尽管指南在 CRS 的管理上存在明显分歧,但所有指南都承认鼻腔气道检查的诊断效用。同时也考虑了自最近发布指南以来在 MEDLINE 索引文章中发表的重要且相关数据,并讨论了未来研究的需求。