重新考虑近期心肌梗死作为静脉溶栓治疗脑卒的禁忌证。
Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis.
机构信息
Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608.
出版信息
Neurology. 2011 May 24;76(21):1838-40. doi: 10.1212/WNL.0b013e31821ccc72. Epub 2011 Apr 13.
OBJECTIVES
We reviewed the literature on IV stroke thrombolysis for patients with recent myocardial infarction (MI).
METHODS
We searched PubMed and Ovid databases, relevant trials, and guidelines.
RESULTS
Only 5 thrombolyzed stroke patients with recent MI were reported to have cardiac tamponade. Pathological studies show MI healing is completed by 7 weeks.
CONCLUSION
The time window from MI as a contraindication for IV stroke thrombolysis may be narrowed from 3 months in current guidelines to 7 weeks.
目的
我们回顾了近期心肌梗死（MI）患者静脉溶栓治疗的相关文献。
方法
我们检索了 PubMed 和 Ovid 数据库、相关试验和指南。
结果
仅有 5 例溶栓治疗的脑卒中合并近期 MI 患者报告有心包填塞。病理学研究表明，MI 愈合在 7 周内完成。
结论
将 MI 作为静脉溶栓治疗禁忌证的时间窗可能会从目前指南中的 3 个月缩短至 7 周。
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