Vera-Cruz Ana, Cerol Marta, Pereira Maria Margarida, Canadas Sónia, Mortágua Juliana, Gherbovetchi Ion, Andrade José Pedro
Medicine Department, Internal Medicine Service, District Hospital of Santarém, Santarém, Portugal.
Medicine Department, Internal Medicine Service, Hospital Sousa Martins, Guarda, Portugal.
Eur J Case Rep Intern Med. 2020 Mar 13;7(4):001534. doi: 10.12890/2020_001534. eCollection 2020.
Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) is the established treatment for acute ischemic stroke and has been highly effective in reducing the neurological deficit. Serious adverse events are not uncommon, with hemorrhage being the major complication. We describe the case of a patient with acute ischemic stroke that also presented with vague cardiac symptoms and was treated with rtPA, which was complicated by a hemopericardium causing cardiac tamponade. Pericardiocentesis was promptly performed, which resulted in rapid resolution of the cardiogenic shock. The patient recovered consciousness within a few minutes. A search of the MEDLINE database shows that this is the first report of cardiac tamponade after rtPA thrombolysis occurring in a patient with no history of recent myocardial infarction or aortic dissection.
Cardiac tamponade is a medical emergency and if not recognized and treated quickly results in cardiogenic shock and death. Hence, it is necessary to be aware that the established treatment for acute ischemic stroke can lead to cardiac tamponade.Cardiac tamponade after rtPA thrombolysis can occur in patients with no history of recent myocardial infarction or aortic dissection.
重组组织型纤溶酶原激活剂(rtPA)静脉溶栓是急性缺血性卒中的既定治疗方法,在减轻神经功能缺损方面非常有效。严重不良事件并不罕见,出血是主要并发症。我们描述了一例急性缺血性卒中患者的病例,该患者还伴有模糊的心脏症状,并接受了rtPA治疗,结果并发血心包导致心脏压塞。立即进行了心包穿刺术,迅速缓解了心源性休克。患者在几分钟内恢复了意识。检索MEDLINE数据库显示,这是首例在无近期心肌梗死或主动脉夹层病史的患者中发生rtPA溶栓后心脏压塞的报告。
心脏压塞是一种医疗急症,如果未被识别并迅速治疗,会导致心源性休克和死亡。因此,有必要意识到急性缺血性卒中的既定治疗方法可能导致心脏压塞。rtPA溶栓后心脏压塞可发生在无近期心肌梗死或主动脉夹层病史的患者中。