Gliem Michael, Panayotopoulos Dimitris, Feindt Peter, Heikaus Sebastian, Fleisch Markus C, Seitz Rüdiger J
Departments of Neurology, Heinrich Heine University, Duesseldorf, Germany.
Case Rep Neurol. 2011 Feb 21;3(1):54-61. doi: 10.1159/000324927.
We report a 66-year-old woman with slowly progressive ataxia due to cerebellar atrophy. Imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space. A biopsy identified the lesions as metastases of a low-grade endometrial stromal sarcoma containing sex-cord elements. The histological appearance was identical to a uterine tumor the patient was treated for with hysterectomy 16 years before. The metastases were removed surgically, and after 3 months ataxia had regressed. We conclude that the presenting cerebellar degeneration in this patient resulted from the metastatic recurrence of the endometrial tumor.
我们报告了一名66岁因小脑萎缩导致缓慢进展性共济失调的女性。影像学检查显示双肺和背侧胸膜下间隙有多个病灶。活检确定这些病灶为含有性索成分的低级别子宫内膜间质肉瘤转移灶。组织学表现与该患者16年前接受子宫切除术治疗的子宫肿瘤相同。转移灶通过手术切除，3个月后共济失调症状消退。我们得出结论，该患者出现的小脑变性是由子宫内膜肿瘤的转移复发所致。
