Rolland Catherine, Broom Iain
Centre for Obesity Research and Epidemiology, Robert Gordon University, St. Andrew Street, Aberdeen AB24 3LR, UK.
Cholesterol. 2011;2011:306278. doi: 10.1155/2011/306278. Epub 2010 Dec 22.
This paper investigates the effects of very-low-calorie diets (VLCDs) used in the treatment of obesity on high-density lipoprotein (HDL) levels. Although the studies varied widely in their intervention format, duration, and baseline HDL levels, it would appear that HDL levels usually decrease during active weight loss using a VLCD, but these either return to pre-VLCD levels or improve overall during the weight-maintenance phase. More research needs to be done to determine optimal weight-maintenance programmes and the effects of VLCDs in the short term as well as on HDL levels in groups at increased risk of coronary heart disease.
本文研究了用于治疗肥胖症的极低热量饮食(VLCD)对高密度脂蛋白(HDL)水平的影响。尽管各项研究在干预形式、持续时间和HDL基线水平方面差异很大,但似乎在使用VLCD进行积极减重期间,HDL水平通常会下降,但这些水平要么恢复到VLCD前的水平,要么在体重维持阶段总体上有所改善。需要开展更多研究以确定最佳的体重维持方案,以及VLCD在短期内的效果及其对冠心病风险增加人群HDL水平的影响。