胎盘早剥的围产期结局是否因临床表现而有所改变？
Is the perinatal outcome of placental abruption modified by clinical presentation?
作者信息
Furukawa Seishi, Sameshima Hiroshi, Ikenoue Tsuyomu, Ohashi Masanao, Nagai Yoshio
机构信息
Department of Obstetric & Gynecology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.
出版信息
J Pregnancy. 2011;2011:659615. doi: 10.1155/2011/659615. Epub 2010 Oct 5.
OBJECTIVE
The purpose of this study was to elucidate the impact of the clinical presentation on perinatal outcome in placental abruption.
STUDY DESIGN
A retrospective study was performed in 97 placental abruptions. Placental abruptions were classified according to clinical presentation: pregnancy-induced hypertension (HT, n = 22), threatened premature labor and/or premature rupture of membranes (TPL/ROM, n = 35), clinically low risk (LR, n = 27), and others (n = 13). Perinatal outcomes were compared among the HT, TPL/ROM, and LR groups.
RESULTS
The HT had significantly higher incidence of IUGR, IFUD, and low fibrinogen. The TPL/ROM had less severe disease. However, the LR had significantly higher incidence of IUFD, low UA pH < 7.1, low Apgar score of <7 at 5 min, and low fibrinogen.
CONCLUSION
Disease severity in placental abruption is likely to depend on the clinical presentation.
目的
本研究旨在阐明胎盘早剥临床表现对围产期结局的影响。
研究设计
对97例胎盘早剥患者进行回顾性研究。胎盘早剥根据临床表现分类：妊娠高血压（HT，n = 22）、先兆早产和/或胎膜早破（TPL/ROM，n = 35）、临床低风险（LR，n = 27）以及其他（n = 13）。比较HT、TPL/ROM和LR组的围产期结局。
结果
HT组胎儿生长受限（IUGR）、胎儿宫内死亡（IFUD）和纤维蛋白原降低的发生率显著更高。TPL/ROM组病情较轻。然而，LR组胎儿宫内死亡（IUFD）、脐动脉pH值<7.1、5分钟时阿氏评分<7以及纤维蛋白原降低的发生率显著更高。
结论
胎盘早剥的疾病严重程度可能取决于临床表现。
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