Berenson A B, Wiemann C M, McCombs S L
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston 77555-0587, USA.
J Reprod Med. 1997 Sep;42(9):559-64.
To determine whether pregnant adolescents < or = 15 years of age developed more perinatal complications than older adolescents or adult women.
We conducted a study of 147 nulliparous adolescents < or = 15 years of age who initiated prenatal care at the University of Texas Medical Branch at Galveston between January 1, 1992, and April 27, 1994. For purposes of analyses, these patients were then compared to two groups: (1) all nulliparas between the ages of 16 and 17 (n = 287) and (2) those 20-22 years old (n = 107) who delivered an infant of > or = 20 weeks' gestation and initiated care during the same interval at this same facility. Chi-square, Kruskall-Wallis or Student's t test initially was used to identify differences between groups in demographic characteristics and perinatal complications. Logistic regression analyses were then performed to determine whether observed differences in outcomes remained while controlling for potentially confounding variables.
Adolescents < or = 15 years of age were more likely to develop anemia and less likely to deliver an infant who required admission to the intensive care unit. No differences were observed between groups in the prevalence of pregnancy-induced hypertension, preterm labor, preterm premature rupture of membranes, chorioamnionitis, meconium staining, endometritis, preterm delivery, low birth weight, low Apgar score or fetal demise.
Adolescents < or = 15 years of age experience perinatal outcomes similar to those of older adolescents and young adult women.
确定15岁及以下的怀孕青少年是否比年龄较大的青少年或成年女性出现更多围产期并发症。
我们对1992年1月1日至1994年4月27日期间在加尔维斯顿的德克萨斯大学医学分校开始产前护理的147名年龄小于或等于15岁的未生育青少年进行了一项研究。为了进行分析,将这些患者与两组进行比较:(1)所有年龄在16至17岁之间的未生育者(n = 287),以及(2)年龄在20至22岁之间(n = 107)、分娩孕周大于或等于20周且在同一时间段内在该机构开始护理的人群。最初使用卡方检验、克鲁斯卡尔-沃利斯检验或学生t检验来确定各组在人口统计学特征和围产期并发症方面的差异。然后进行逻辑回归分析,以确定在控制潜在混杂变量的情况下,观察到的结果差异是否仍然存在。
15岁及以下的青少年更易患贫血,而分娩时需要入住重症监护病房的婴儿较少。在妊娠高血压、早产、胎膜早破、绒毛膜羊膜炎、胎粪污染、子宫内膜炎、早产、低出生体重、阿氏评分低或胎儿死亡的患病率方面,各组之间未观察到差异。
15岁及以下的青少年的围产期结局与年龄较大的青少年和年轻成年女性相似。