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吸入性糖皮质激素治疗孤立性胃克罗恩病

Treatment of isolated gastric Crohn's disease with inhaled corticosteroids.

作者信息

Ibrahim Samar H, Smyrk Thomas C, Faubion William A

机构信息

Pediatric and Adolescent Medicine Department, Mayo Clinic, Rochester, Minn., USA.

出版信息

Case Rep Gastroenterol. 2008 Nov 5;2(3):363-8. doi: 10.1159/000158543.

DOI:10.1159/000158543
PMID:21490870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3075198/
Abstract

Isolated gastric Crohn's disease is unusual and a rare cause of pyloric outlet obstruction. If medical therapy is ineffective, patients may require surgery to relieve gastric outlet obstruction. Herein we describe a patient with isolated gastric Crohn's disease with pyloric outlet obstruction who was steroid-dependent and had a relapse despite receiving biologic and immunomodulatory therapy, but ultimately responded to topical treatment with inhaled corticosteroids.

摘要

孤立性胃克罗恩病较为罕见,是幽门出口梗阻的少见病因。若药物治疗无效,患者可能需要手术来缓解胃出口梗阻。在此,我们描述一名患有孤立性胃克罗恩病伴幽门出口梗阻的患者,该患者依赖类固醇,尽管接受了生物制剂和免疫调节治疗仍复发,但最终对吸入性糖皮质激素局部治疗有反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/79d880d877f5/crg0002-0363-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/fac1c5609e5e/crg0002-0363-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/0fabe75af81c/crg0002-0363-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/79d880d877f5/crg0002-0363-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/fac1c5609e5e/crg0002-0363-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/0fabe75af81c/crg0002-0363-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed56/3075198/79d880d877f5/crg0002-0363-f03.jpg

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Pragmat Obs Res. 2024 Feb 21;15:17-29. doi: 10.2147/POR.S444569. eCollection 2024.
3
Crohn's disease: An enigmatic variant with gastritis and ileal obstruction.克罗恩病:一种伴有胃炎和肠梗阻的神秘变体。

本文引用的文献

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Successful infliximab therapy for a duodenal stricture caused by Crohn's disease.英夫利昔单抗成功治疗克罗恩病引起的十二指肠狭窄。
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Crohn's disease presenting as gastric outlet obstruction: a therapeutic challenge?以胃出口梗阻为表现的克罗恩病:一项治疗挑战?
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Gastroduodenal Crohn's disease: medical management.胃十二指肠克罗恩病:药物治疗
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