Gaggar Sameer, Scott John, Thompson Nicholas
Sameer Gaggar, Nicholas Thompson, Department of Gastroenterology, Freeman Hospital, NE7 7DN Newcastle, United Kingdom.
World J Gastrointest Pharmacol Ther. 2012 Dec 6;3(6):97-9. doi: 10.4292/wjgpt.v3.i6.97.
Gastroduodenal Crohn's disease (CD) is rare and the response to standard medical therapy is often poor. Anti-tumor necrosis factor therapy has revolutionised the treatment of CD. We present a patient with pyloric stenosis associated with CD which improved with Adalimumab therapy. We recommend considering anti-tumor necrosis factor therapy in symptomatic gastroduodenal CD.
胃十二指肠克罗恩病(CD)较为罕见,对标准药物治疗的反应通常较差。抗肿瘤坏死因子疗法彻底改变了CD的治疗方式。我们报告了1例与CD相关的幽门狭窄患者,其经阿达木单抗治疗后病情改善。我们建议对有症状的胃十二指肠CD考虑采用抗肿瘤坏死因子疗法。