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幽门狭窄合并克罗恩病对阿达木单抗治疗有反应。

Pyloric stenosis associated Crohn's disease responding to adalimumab therapy.

作者信息

Gaggar Sameer, Scott John, Thompson Nicholas

机构信息

Sameer Gaggar, Nicholas Thompson, Department of Gastroenterology, Freeman Hospital, NE7 7DN Newcastle, United Kingdom.

出版信息

World J Gastrointest Pharmacol Ther. 2012 Dec 6;3(6):97-9. doi: 10.4292/wjgpt.v3.i6.97.

DOI:10.4292/wjgpt.v3.i6.97
PMID:23494865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3596519/
Abstract

Gastroduodenal Crohn's disease (CD) is rare and the response to standard medical therapy is often poor. Anti-tumor necrosis factor therapy has revolutionised the treatment of CD. We present a patient with pyloric stenosis associated with CD which improved with Adalimumab therapy. We recommend considering anti-tumor necrosis factor therapy in symptomatic gastroduodenal CD.

摘要

胃十二指肠克罗恩病（CD）较为罕见，对标准药物治疗的反应通常较差。抗肿瘤坏死因子疗法彻底改变了CD的治疗方式。我们报告了1例与CD相关的幽门狭窄患者，其经阿达木单抗治疗后病情改善。我们建议对有症状的胃十二指肠CD考虑采用抗肿瘤坏死因子疗法。

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本文引用的文献

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Treatment of isolated gastric Crohn's disease with inhaled corticosteroids.吸入性糖皮质激素治疗孤立性胃克罗恩病
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Duodenal Crohn's disease successfully treated with adalimumab.阿达木单抗成功治疗十二指肠克罗恩病。
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Thyroid function tests: a review.甲状腺功能检查：综述。
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Successful treatment of refractory duodenal Crohn's disease with infliximab.英夫利昔单抗成功治疗难治性十二指肠克罗恩病
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Successful infliximab therapy for a duodenal stricture caused by Crohn's disease.英夫利昔单抗成功治疗克罗恩病引起的十二指肠狭窄。
Inflamm Bowel Dis. 2005 Dec;11(12):1123-5. doi: 10.1097/01.mib.0000191612.43584.94.
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Role of strictureplasty in surgical treatment of Crohn's disease.狭窄成形术在克罗恩病外科治疗中的作用。
J Gastroenterol. 2005 Mar;40 Suppl 16:35-9. doi: 10.1007/BF02990577.
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