Kwena Zachary A, Cohen Craig R, Sang Norton M, Ng'ayo Musa O, Ochieng Jeremiah H, Bukusi Elizabeth A
Research Care and Treatment Program, Center for Microbiology Research, Kenya Medical Research Institute, Lumumba Health Center, P.O. Box 614, 40100, Kisumu, Nairobi, Kenya.
AIDS Res Treat. 2010;2010:865903. doi: 10.1155/2010/865903. Epub 2010 Jul 18.
Background. Suitable populations to sustain continued evaluation of HIV and sexually transmitted infection (STI) prevention interventions are required. We sought to determine whether fishermen are a suitable population for HIV intervention trials. Methods. In a cross-sectional descriptive survey, we selected 250 fishermen from proportional to size sampled boats. We collected socioeconomic and behavioral information, and specimens for HIV, herpes simplex virus (HSV-2), syphilis, gonorrhea, chlamydia and human papillomavirus (HPV) tests from consenting participants. Results. One third of the fishermen had concurrent sexual partnerships and two thirds were involved in transactional sex. About 70% were involved in extramarital sex with only one quarter using condoms in their three most recent sexual encounters. HIV prevalence was 26% and HSV-2 and HPV was 57%. Over 98% were willing to participate in a future HIV prevention clinical trial. Conclusion. Fishermen are a high-risk group for HIV/STI infections that may be suitable for HIV prevention trials. A cohort study would be useful to measure the incidence of HIV/STIs to ultimately determine the feasibility of enrolling this population in an HIV/STI prevention clinical trial.
背景。需要有合适的人群来持续评估艾滋病毒和性传播感染(STI)预防干预措施。我们试图确定渔民是否是适合进行艾滋病毒干预试验的人群。方法。在一项横断面描述性调查中,我们从按比例抽样的船只中挑选了250名渔民。我们收集了社会经济和行为信息,并从同意参与的参与者那里采集了用于艾滋病毒、单纯疱疹病毒2型(HSV-2)、梅毒、淋病、衣原体和人乳头瘤病毒(HPV)检测的标本。结果。三分之一的渔民有同时存在的性伴侣关系,三分之二参与了交易性行为。约70%的人有婚外性行为,在他们最近的三次性接触中只有四分之一的人使用了避孕套。艾滋病毒感染率为26%,HSV-2和HPV感染率为57%。超过98%的人愿意参加未来的艾滋病毒预防临床试验。结论。渔民是艾滋病毒/性传播感染的高危人群,可能适合进行艾滋病毒预防试验。队列研究将有助于测量艾滋病毒/性传播感染的发病率,以最终确定将该人群纳入艾滋病毒/性传播感染预防临床试验的可行性。