家鸽的羽毛角蛋白基因多态性（F-KER）。

Feather keratin gene polymorphism (F-KER) in domestic pigeons.

West Pomeranian University of Technology, Laboratory of Molecular Cytogenetics, 71-460 Szczecin, Poland.

Br Poult Sci. 2011 Apr;52(2):173-6. doi: 10.1080/00071668.2010.549666.

Abstract

A 525-bp fragment of a feather keratin (F-KER) gene was amplified. Four PCR products were sequenced. 2. Two substitutions in the amplified region were observed, one of them in the coding region of the gene (cysteine to glycine substitution in the protein). A new ACRS-PCR test for AvaI enzyme was designed. A total of 344 domestic pigeons (Columba livia var. domestica) were genotyped. 3. There were significant differences in the frequencies of alleles and genotypes between homing and non-homing pigeons. The frequency of the rare F-KER(G) allele was higher in the group of homing pigeons. 4. The effects of the detected polymorphism on flying performance should be verified in biomechanical studies.

摘要

扩增了一段 525 个碱基的羽毛角蛋白（F-KER）基因片段。对四个 PCR 产物进行了测序。
在扩增区域观察到两个取代，其中一个发生在基因的编码区（蛋白质中的半胱氨酸到甘氨酸取代）。设计了一种新的 AvaI 酶 ACRS-PCR 检测方法。对 344 只家鸽（Columba livia var. domestica）进行了基因分型。
在归巢和非归巢鸽子之间，等位基因和基因型的频率存在显著差异。归巢鸽子组中罕见的 F-KER(G)等位基因的频率更高。
应该在生物力学研究中验证检测到的多态性对飞行性能的影响。