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[鼻窦血管外皮细胞瘤:4例病例回顾]

[Sinonasal hemangiopericytoma: review of four cases].

作者信息

Luna B Azoulay, Chraibi M, Abd I Alsamad, Coste A, Babin E

机构信息

CHU de Caen, Service d'ORL et de Chirurgie Cervico-Faciale, Avenue de la Cote de Nacre, 14000 Caen, France.

出版信息

Rev Laryngol Otol Rhinol (Bord). 2010;131(3):207-12.

Abstract

AIM

The aim of this paper is to discuss, through four cases, the characteristics of sinonasal hemangiopericytoma (SNHP) and its diagnostic difficulties.

MATERIALS AND METHODS

Description of four recent, histologically proven cases of SNHP. Bibliographic research was conducted using the following principal key word: "sinonasal hemangiopericytoma".

RESULTS

The four patients complained of non-specific rhino-sinusal symptoms. In each case, physical examination revealed a voluminous unilateral polyploïd tumour of the nasal cavities, documented by CT Scan and MRI. Each patient underwent complete tumour resection by endoscopic sinus surgery. Histological and immunohistochemical examination confirmed SNHP diagnosis, although no specific marker was constantly observed. To date, none of the patients has presented with recurrence.

CONCLUSION

SNHP is of poorly specific clinical and histological presentation. This tumour is difficult to distinguish from solitary fibrous tumour (SFT), with which it is often confused. SNHP is of good prognosis, however lifelong follow-up must be observed.

摘要

目的

本文旨在通过四个病例探讨鼻窦血管外皮细胞瘤(SNHP)的特征及其诊断难点。

材料与方法

描述近期经组织学证实的四例SNHP病例。使用以下主要关键词进行文献检索:“鼻窦血管外皮细胞瘤”。

结果

四名患者均主诉有非特异性鼻-鼻窦症状。在每例病例中,体格检查均发现鼻腔有一个巨大的单侧息肉样肿瘤,CT扫描和MRI证实了这一点。每位患者均通过鼻内镜鼻窦手术进行了肿瘤全切术。组织学和免疫组化检查确诊为SNHP,尽管未发现始终存在的特异性标志物。迄今为止,尚无患者出现复发。

结论

SNHP的临床和组织学表现特异性较差。该肿瘤难以与常与之混淆的孤立性纤维瘤(SFT)相区分。然而,SNHP预后良好,必须进行终身随访。

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