Guangdong Provincial Center for Disease Control and Prevention, No. 176 Xingang West Road, Guangzhou, Guangdong Province, People's Republic of China.
Foodborne Pathog Dis. 2012 Apr;9(4):305-12. doi: 10.1089/fpd.2011.1008. Epub 2012 Feb 22.
Salmonella is one of the most common foodborne pathogens in humans. Laboratory-based surveillance for non-typhoidal Salmonella infection was conducted in Guangdong Province, China to improve understanding about the disease burden and detection of dispersed outbreaks. Salmonella isolated from patients with diarrhea were sent from 16 sentinel hospitals to local public health laboratories for confirmation, serotyping, antimicrobial susceptibility testing, and pulsed-field gel electrophoresis (PFGE). PFGE patterns were analyzed to identify clusters representing potential outbreaks. Between September 2009 and October 2010, 352 (4%) Salmonella isolates were obtained from 9167 stool specimens. Salmonella enterica serotype Typhimurium (45%) and Salmonella enterica serotype Enteritidis (13%) were the most common serotypes, and multidrug resistance was high, especially in Salmonella Typhimurium isolates. PFGE patterns of obtained Salmonella isolates were found to be diverse, but a unique PFGE pattern comprising 53 Salmonella Typhimurium isolates were found to occur almost exclusively in infants. Epidemiologic studies are ongoing to determine whether a common exposure is the source of the Salmonella Typhimurium strain frequently isolated from infants.
沙门氏菌是人类中最常见的食源性病原体之一。为了更好地了解疾病负担和发现分散的暴发疫情，在中国广东省开展了基于实验室的非伤寒沙门氏菌感染监测。从腹泻患者中分离出的沙门氏菌从 16 家哨点医院送到当地公共卫生实验室进行确认、血清分型、药敏试验和脉冲场凝胶电泳（PFGE）。PFGE 图谱用于识别代表潜在暴发的聚类。2009 年 9 月至 2010 年 10 月，从 9167 份粪便标本中获得了 352 株（4%）沙门氏菌分离株。肠炎沙门氏菌（45%）和肠炎沙门氏菌（13%）是最常见的血清型，且多药耐药性很高，尤其是在鼠伤寒沙门氏菌分离株中。获得的沙门氏菌分离株的 PFGE 图谱发现具有多样性，但发现一种独特的 PFGE 图谱包含 53 株鼠伤寒沙门氏菌分离株几乎只存在于婴儿中。正在进行流行病学研究，以确定是否存在共同暴露是婴儿中经常分离到的鼠伤寒沙门氏菌菌株的来源。
