Tissugen Pty Ltd, Perth, Western Australia.
BJU Int. 2011 Apr;107 Suppl 3:24-6. doi: 10.1111/j.1464-410X.2011.10046.x.
• To compare the clinical and pathological details of inverted papilloma (IP) of the urinary tract diagnosed in Western Australia with those published. • To determine whether urinary tract IP requires post-treatment cystoscopic follow-up.
• Clinical and pathological details were summarized for 41 cases of IP of the urinary tract diagnosed in Western Australia between 1998 and 2010. • Publications on IP of the urinary tract were reviewed and summarized.
• IP of the urinary tract is a rare benign tumour most commonly diagnosed in older men presenting with haematuria or symptoms of lower urinary tract obstruction. • IP is most frequently identified in the bladder neck or trigone as a polypoid growth with a smooth surface. • The major differential diagnosis is transitional cell carcinoma (TCC) with an inverted growth pattern, with differentiation based mainly on morphological criteria. • Treatment involves transurethral resection for lower urinary tract lesions whereas upper urinary tract IPs are resected by ureteroscopy, percutaneous endoscopy, partial ureterectomy or nephroureterectomy. • IP is weakly associated with a history of TCC and with increased risk of concomitant or subsequent TCC.
• Based on the association with TCC, post-treatment follow-up for IP of the urinary tract should include cystoscopic follow-up.
比较在澳大利亚西部诊断出的尿路内翻性乳头状瘤（IP）的临床和病理细节与已发表的结果。
确定尿路 IP 是否需要治疗后膀胱镜随访。
总结了 1998 年至 2010 年间在澳大利亚西部诊断出的 41 例尿路 IP 的临床和病理细节。
回顾并总结了关于尿路 IP 的出版物。
尿路 IP 是一种罕见的良性肿瘤，最常见于出现血尿或下尿路梗阻症状的老年男性。
IP 最常发生在膀胱颈部或三角区，呈息肉样生长，表面光滑。
主要的鉴别诊断是具有倒置生长模式的移行细胞癌（TCC），主要基于形态学标准进行区分。
治疗包括经尿道切除用于下尿路病变，而上尿路 IP 则通过输尿管镜、经皮内镜、部分输尿管切除术或肾输尿管切除术切除。
IP 与 TCC 病史弱相关，并发或随后发生 TCC 的风险增加。
