Ouskri Salim, Kadouri Youssef, Lakssir Jihad, Boualaoui Imad, El Sayegh Hachem, Nouini Yassine
Ibn Sina Hospital, Morocco.
Ibn Sina Hospital, Morocco.
Int J Surg Case Rep. 2025 Jun;131:111374. doi: 10.1016/j.ijscr.2025.111374. Epub 2025 Apr 25.
Bladder inverted papilloma (IP) is a rare benign urothelial lesion, representing 1-2.2 % of all bladder tumors. Although benign, IP can coexist with urothelial carcinoma, necessitating careful long-term follow-up.
A 63-year-old male, chronic smoker presented with macroscopic hematuria and irritative urinary symptoms. Imaging and cystoscopy revealed multiple bladder polyps. Complete transurethral resection was performed, and histopathological examination confirmed the diagnosis of inverted papilloma. Follow-up cystoscopy at three months showed no recurrence.
Inverted papilloma commonly affects older males, typically presenting with hematuria or obstructive symptoms. Diagnosis requires histopathological confirmation demonstrating endophytic proliferation of urothelium without atypia. The risk of synchronous or subsequent urothelial carcinoma, particularly in the upper urinary tract, emphasizes the need for regular cystoscopic surveillance.
Despite its benign nature, IP demands careful monitoring due to potential malignant associations. Endoscopic resection remains the standard treatment, followed by routine cystoscopic surveillance.
膀胱内翻性乳头状瘤（IP）是一种罕见的良性尿路上皮病变，占所有膀胱肿瘤的1%-2.2%。尽管为良性，但IP可与尿路上皮癌共存，因此需要进行仔细的长期随访。
一名63岁男性，长期吸烟，出现肉眼血尿和刺激性尿路症状。影像学检查和膀胱镜检查发现多个膀胱息肉。进行了经尿道完全切除术，组织病理学检查确诊为内翻性乳头状瘤。三个月后的随访膀胱镜检查显示无复发。
内翻性乳头状瘤通常影响老年男性，典型表现为血尿或梗阻症状。诊断需要组织病理学证实显示尿路上皮内生性增生且无异型性。同步或后续发生尿路上皮癌的风险，尤其是在上尿路，强调了定期膀胱镜监测的必要性。
尽管IP本质为良性，但由于可能存在恶性关联，仍需仔细监测。内镜切除仍然是标准治疗方法，随后进行常规膀胱镜监测。
