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后交通动脉真性动脉瘤:个体患者数据的系统评价和荟萃分析。

True aneurysms of the posterior communicating artery: a systematic review and meta-analysis of individual patient data.

机构信息

Department of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.

出版信息

World Neurosurg. 2011 Jan;75(1):64-72; discussion 49. doi: 10.1016/j.wneu.2010.09.012.

DOI:10.1016/j.wneu.2010.09.012
PMID:21492665
Abstract

OBJECTIVE

To review and analyze systematically the reported cases of "true" posterior communicating artery (PCoA) aneurysm.

METHODS

A retrospective review of the published literature was performed, and a meta-analysis of individual patient data was conducted.

RESULTS

Pooled data showed that "true" PCoA aneurysms represent about 1.3% (95% confidence interval [CI] 0.8%, 1.7%) of all intracranial aneurysms and 6.8% (95% CI 4.3%, 9.2%) of all PCoA aneurysms. Mean patient age was 53.5 years (53.5 years ± 15.4), and age range was 23-79 years. Of the 49 patients reported in the literature, 44 (89.8%) were reported as ruptured, and 4 (10.2%) were reported as unruptured. There were no significant differences in ruptured status between age (P = 0.321), left vs right aneurysm (P = 0.537), and shape of aneurysm (P = 0.408). No significant differences in complication rates were found between rupture status (P = 0.27), and operative modalities (P = 0.878). The mean ages of patients who had no complications and patients who had complications were 53 years (53 years ± 2.59) vs 53.2 years (53.2 years ± 5.02) (P = 0.972).

CONCLUSIONS

"True" PCoA aneurysms represent about 1.3% of all intracranial aneurysms and 6.8% of all PCoA aneurysms. They are more prone to rupture compared with their counterpart junctional aneurysms. When surgical management is indicated, a good understanding of the location and configuration of the aneurysm neck before surgical treatment is critical in the successful treatment of these lesions.

摘要

目的

系统回顾和分析报道的“真性”后交通动脉(PCoA)动脉瘤病例。

方法

对已发表文献进行回顾性分析,并对个体患者数据进行荟萃分析。

结果

汇总数据显示,“真性”PCoA 动脉瘤占所有颅内动脉瘤的 1.3%(95%置信区间 [CI]:0.8%,1.7%),占所有 PCoA 动脉瘤的 6.8%(95%CI:4.3%,9.2%)。患者平均年龄为 53.5 岁(53.5 岁±15.4 岁),年龄范围为 23-79 岁。文献报道的 49 例患者中,44 例(89.8%)为破裂性动脉瘤,4 例(10.2%)为未破裂性动脉瘤。在破裂状态方面,年龄(P=0.321)、左侧与右侧动脉瘤(P=0.537)和动脉瘤形态(P=0.408)之间无显著差异。破裂状态(P=0.27)和手术方式(P=0.878)之间的并发症发生率也无显著差异。无并发症患者和有并发症患者的平均年龄分别为 53 岁(53 岁±2.59)和 53.2 岁(53.2 岁±5.02)(P=0.972)。

结论

“真性”PCoA 动脉瘤占所有颅内动脉瘤的 1.3%,占所有 PCoA 动脉瘤的 6.8%。与相应的交界性动脉瘤相比,“真性”PCoA 动脉瘤更易破裂。当需要手术治疗时,在手术治疗前充分了解动脉瘤颈的位置和形态对于成功治疗这些病变至关重要。

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