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脊髓神经根鞘内脊柱脑膜黑色素细胞瘤伴脊柱旁延伸,类似于神经鞘瘤。

Spinal meningeal melanocytoma in the S-1 nerve root sheath with paraspinal extension mimicking schwannoma.

机构信息

Department of Orthopedic Surgery, Wooridul Spine Hospital, Seoul, Korea.

出版信息

World Neurosurg. 2011 Feb;75(2):303-6. doi: 10.1016/j.wneu.2010.06.034.

Abstract

BACKGROUND

Spinal melanocytomas are variants that can be extradural or intradural and are most often located in the intradural extramedullary compartment of the main thecal sac as in schwannomas. However, origin of this variant from the pure peripheral compartment of rootlets is exceedingly rare.

CASE DESCRIPTION

The authors present a case of spinal melanocytoma with confusing pathologic and radiologic features. This patient presented clinically with severe radiating pain on the right lower extremity. Before surgery, clinical and radiologic findings were consistent with a schwannoma. However, on operation, a coal-black pigmented lesion mimicking old blood clot was found inside the right S-1 root sheath, attached to the dura. The mass was completely removed and consequently the patient's symptoms improved.

CONCLUSIONS

The spinal melanocytoma should be included as a differential diagnosis before giving a presumptive diagnosis of schwannoma or hemorrhage for the patient with a space-occupying lesion at a peripheral rootlet. Intraoperative gross morphology and histopathologic findings facilitate differential diagnosis.

摘要

背景

脊髓黑色素细胞瘤是一种变体,可分为硬膜外或硬膜内,最常见于硬脊膜内髓外腔,类似于神经鞘瘤。然而,这种变体起源于单纯的神经根周围部位极为罕见。

病例描述

作者报告了一例脊髓黑色素细胞瘤,其具有混淆的病理和影像学特征。该患者表现为右下肢严重放射性疼痛的临床症状。在手术前,临床和影像学检查结果与神经鞘瘤一致。然而,在手术中,发现附着于硬脑膜的右侧 S-1 神经根鞘内有一个类似陈旧血斑的深黑色色素病变。该肿块被完全切除,患者的症状随后得到改善。

结论

对于位于神经根周围部位有占位性病变的患者,在给出神经鞘瘤或出血的推测诊断之前,应将脊髓黑色素细胞瘤纳入鉴别诊断。术中大体形态和组织病理学发现有助于鉴别诊断。

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