Poggi P, Marchetti C, Scelsi R, Calligaro A, Casasco A
Dipartimento di Patologia Umana ed Ereditaria, Università di Pavia, Italia.
J Submicrosc Cytol Pathol. 1990 Oct;22(4):515-21.
The organogenesis of the rat diaphragm was studied with enzyme-histochemical, ultrastructural and morphometrical methods. 18 to 20 and 22 day in utero diaphragms were examined as well as 2-8-14 and 25 day old ones, in order to determine the age related changes in the diameter and the percentage of muscle fibers and mitochondria. In all examined ages, morphometric data showed type II fiber predominance. Type I and II fibers were equivalent in diameter. During fetal life, mitochondrial size increases appreciably with age while the mitochondrial percentage does not. Instead in postnatal life, the mitochondrial diameter is almost constant both for the small type I fibers and for the large ones (type II fibers). The mitochondrial percentage gradually increases particularly in the small fibers.
采用酶组织化学、超微结构和形态计量学方法研究了大鼠膈肌的器官发生。对子宫内18至20天和22天的膈肌以及2至8、14和25日龄的膈肌进行了检查,以确定肌纤维和线粒体直径及百分比与年龄相关的变化。在所有检查的年龄中,形态计量学数据显示II型纤维占优势。I型和II型纤维直径相当。在胎儿期,线粒体大小随年龄显著增加,而线粒体百分比则不然。相反,在出生后,无论是小的I型纤维还是大的(II型纤维),线粒体直径几乎恒定。线粒体百分比逐渐增加,尤其是在小纤维中。