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Z 成形软腭咽成形术联合颏舌肌前移和舌骨悬吊术治疗阻塞性睡眠呼吸暂停低通气综合征。

Z-palatopharyngoplasty plus genioglossus advancement and hyoid suspension for obstructive sleep apnea hypopnea syndrome.

机构信息

Department of Otolaryngology, Affiliated Sixth People's Hospital, Otolaryngology Institute, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Otolaryngol Head Neck Surg. 2011 Mar;144(3):469-73. doi: 10.1177/0194599810393116. Epub 2011 Feb 4.

Abstract

OBJECTIVE

To explore the feasibility and efficiency of Z-palato-pharyngoplasty (ZPPP) plus genioglossus advancement and hyoid suspension (GAHM) for severe obstructive sleep apnea hypopnea syndrome (OSAHS).

STUDY DESIGN

Case series with planned data collection.

SETTING

A university medical center.

SUBJECTS AND METHODS

Twenty-six patients who had OSAHS with Friedman obstructive sleep apnea stage II/III and posterior airway space <11 mm received GAHM and ZPPP. All patients were reevaluated 6 months after surgery using the preoperative methods.

RESULTS

Based on success criteria, defined as an apnea-hypopnea index (AHI) of <20 and a decrease >50%, the success rate was 46.2% at 6 months postoperatively. The AHI showed a significant reduction from 65.6 ± 17.6 preoperatively to 30.1 ± 23.1 postoperatively. The percentage of time with oxyhemoglobin saturation below 90% (CT(90)) decreased from 30.9% ± 28.1% preoperatively to 15.5% ± 25.6% postoperatively (P < .01). Sleep architecture was effectively changed. The S3 + S4 percentage of total sleep time increased from 3.6% ± 4.4% to 8.7% ± 5.0% (P < .05). The success rates were 100% (8/8) and 22.2% (4/18) in patients with Friedman obstructive sleep apnea stage II and III, respectively.

CONCLUSION

The success rate of ZPPP plus GAHM for patients with severe OSAHS who suffer from oropharyngeal and hypopharyngeal obstruction was limited. Friedman stage was a predictor of ZPPP plus GAHM surgical success.

摘要

目的

探讨 Z 成形腭咽成形术(ZPPP)联合颏舌肌前移和舌骨悬吊术(GAHM)治疗重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的可行性和疗效。

研究设计

有计划数据收集的病例系列。

设置

一所大学医学中心。

受试者和方法

26 例 OSAHS 患者,Friedman 阻塞性睡眠呼吸暂停分期 II/III 期,后气道空间<11mm,行 GAHM 和 ZPPP。所有患者均在术后 6 个月采用术前方法进行再次评估。

结果

根据定义为 AHI<20 和下降>50%的成功标准,术后 6 个月的成功率为 46.2%。AHI 从术前的 65.6±17.6 显著降低至术后的 30.1±23.1。氧合血红蛋白饱和度低于 90%(CT(90))的时间百分比从术前的 30.9%±28.1%降至术后的 15.5%±25.6%(P<0.01)。睡眠结构得到有效改善。S3+S4 占总睡眠时间的百分比从 3.6%±4.4%增加到 8.7%±5.0%(P<0.05)。Friedman 阻塞性睡眠呼吸暂停分期 II 期和 III 期患者的成功率分别为 100%(8/8)和 22.2%(4/18)。

结论

ZPPP 联合 GAHM 治疗伴有口咽和下咽阻塞的重度 OSAHS 患者的成功率有限。Friedman 分期是 ZPPP 联合 GAHM 手术成功的预测因素。

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