Cillo Joseph E, Dalton Patrick S, Dattilo David J
Assistant Professor and Program Director, Division of Oral and Maxillofacial Surgery, Allegheny General Hospital, Allegheny Health Network, Pittsburgh, PA.
J Oral Maxillofac Surg. 2013 Oct;71(10):1729-32. doi: 10.1016/j.joms.2013.06.001. Epub 2013 Aug 8.
The objective and subjective outcomes of combined mandibular elliptical window genioglossus advancement, hyoid bone suspension, and uvulopalatopharyngoplasty procedures have not been evaluated. This study was conducted to evaluate postoperative changes in the apnea hypopnea index (AHI) and subjective daytime sleepiness with this combination of procedures in the surgical management of obstructive sleep apnea (OSA).
This was a retrospective cohort analysis of patients who had undergone combined elliptical window genioglossus advancement, hyoid bone suspension, and uvulopalatopharyngoplasty performed at Allegheny General Hospital (Pittsburgh, PA) from July 1, 2006 through December 31, 2008 for polysomnogram-confirmed OSA. Inclusion criteria included patients who had undergone the combined elliptical window genioglossus advancement, hyoid bone suspension, and uvulopalatopharyngoplasty procedures with preoperative and minimum 6-month postoperative AHI and Epworth Sleepiness Scale (ESS). Statistical significance between mean differences of pre- and postoperative AHI and ESS was determined with the 2-tailed paired t test and 95% confidence intervals.
Thirteen male patients (average age, 43.0 ± 2.4 yr; average follow-up, 18.0 ± 3.6 months) were included in this study. There were statistically significant differences between mean pre- and postoperative AHI (28.3 vs 12.1; P < .05; mean change, -16.2; 57.2% decrease) and ESS (15.2 vs 6.3; P < .05; mean change, -8.9; 58.6% decrease).
The combined mandibular elliptical window genioglossus advancement, hyoid bone suspension, and uvulopalatopharyngoplasty procedures for the treatment of OSA decrease AHI and subjective daytime sleepiness.
联合下颌椭圆窗颏舌肌前移、舌骨悬吊和悬雍垂腭咽成形术的客观和主观疗效尚未得到评估。本研究旨在评估在阻塞性睡眠呼吸暂停(OSA)的外科治疗中,采用该联合手术方法后呼吸暂停低通气指数(AHI)的术后变化以及主观日间嗜睡情况。
这是一项对2006年7月1日至2008年12月31日在阿勒格尼综合医院(宾夕法尼亚州匹兹堡)接受联合椭圆窗颏舌肌前移、舌骨悬吊和悬雍垂腭咽成形术治疗且多导睡眠图确诊为OSA的患者进行的回顾性队列分析。纳入标准包括接受联合椭圆窗颏舌肌前移、舌骨悬吊和悬雍垂腭咽成形术且术前及术后至少6个月有AHI和爱泼沃斯嗜睡量表(ESS)数据的患者。术前和术后AHI及ESS平均差异的统计学显著性采用双侧配对t检验和95%置信区间确定。
本研究纳入了13例男性患者(平均年龄43.0±2.4岁;平均随访时间18.0±3.6个月)。术前和术后AHI平均水平(28.3对12.1;P<.05;平均变化,-16.2;降低57.2%)及ESS平均水平(15.2对6.3;P<.05;平均变化,-8.9;降低58.6%)之间存在统计学显著差异。
联合下颌椭圆窗颏舌肌前移、舌骨悬吊和悬雍垂腭咽成形术治疗OSA可降低AHI及主观日间嗜睡程度。