Third-hit signaling in renal cyst formation.
作者信息
Weimbs Thomas
出版信息
J Am Soc Nephrol. 2011 May;22(5):793-5. doi: 10.1681/ASN.2011030284. Epub 2011 Apr 14.
Abstract
摘要
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本文引用的文献
1
Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.原发性纤毛丧失会上调肾脏肥大信号通路并促进囊肿形成。
J Am Soc Nephrol. 2011 May;22(5):839-48. doi: 10.1681/ASN.2010050526. Epub 2011 Apr 14.
2
Primary cilia regulate mTORC1 activity and cell size through Lkb1.初级纤毛通过 Lkb1 调节 mTORC1 活性和细胞大小。
Nat Cell Biol. 2010 Nov;12(11):1115-22. doi: 10.1038/ncb2117. Epub 2010 Oct 24.
3
Genetic variation of DKK3 may modify renal disease severity in ADPKD.DKK3 的遗传变异可能会改变 ADPKD 患者的肾脏疾病严重程度。
J Am Soc Nephrol. 2010 Sep;21(9):1510-20. doi: 10.1681/ASN.2010030237. Epub 2010 Jul 8.
4
Incompletely penetrant PKD1 alleles mimic the renal manifestations of ARPKD.不完全外显的 PKD1 等位基因模拟 ARPKD 的肾脏表现。
J Am Soc Nephrol. 2010 Jul;21(7):1097-102. doi: 10.1681/ASN.2009101070. Epub 2010 Jun 17.
5
What is the role of somatic mutation in autosomal dominant polycystic kidney disease?体细胞突变在常染色体显性多囊肾病中起什么作用？
J Am Soc Nephrol. 2010 Jul;21(7):1073-6. doi: 10.1681/ASN.2010030328. Epub 2010 May 20.
6
Molecular advances in autosomal dominant polycystic kidney disease.常染色体显性遗传性多囊肾病的分子进展。
Adv Chronic Kidney Dis. 2010 Mar;17(2):118-30. doi: 10.1053/j.ackd.2010.01.002.
7
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1.雷帕霉素改善条件性 Pkd1 基因敲除引起的 PKD。
J Am Soc Nephrol. 2010 Mar;21(3):489-97. doi: 10.1681/ASN.2009040421. Epub 2010 Jan 14.
8
Centrioles, centrosomes, and cilia in health and disease.健康与疾病中的中心粒、中心体和纤毛。
Cell. 2009 Nov 13;139(4):663-78. doi: 10.1016/j.cell.2009.10.036.
9
The role of the mammalian target of rapamycin (mTOR) in renal disease.雷帕霉素哺乳动物靶点（mTOR）在肾脏疾病中的作用。
J Am Soc Nephrol. 2009 Dec;20(12):2493-502. doi: 10.1681/ASN.2008111186. Epub 2009 Oct 29.
10
Pkd1 haploinsufficiency increases renal damage and induces microcyst formation following ischemia/reperfusion.多囊蛋白1单倍剂量不足会增加肾脏损伤，并在缺血/再灌注后诱导微囊肿形成。
J Am Soc Nephrol. 2009 Nov;20(11):2389-402. doi: 10.1681/ASN.2008040435. Epub 2009 Oct 15.
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