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本文引用的文献

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Effectiveness of HIV prevention for youth in sub-Saharan Africa: systematic review and meta-analysis of randomized and nonrandomized trials.撒哈拉以南非洲地区青少年艾滋病预防的有效性:随机和非随机试验的系统评价和荟萃分析。
AIDS. 2010 May 15;24(8):1193-202. doi: 10.1097/QAD.0b013e3283384791.
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Trends in primary and secondary abstinence among Kenyan youth.肯尼亚青年中初次和再次禁欲的趋势。
AIDS Care. 2009 Jul;21(7):881-92. doi: 10.1080/09540120802537856.
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The short-term impacts of a schooling conditional cash transfer program on the sexual behavior of young women.学校教育有条件现金转移支付计划对年轻女性性行为的短期影响。
Health Econ. 2010 Sep;19 Suppl:55-68. doi: 10.1002/hec.1569.
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Skin disease among human immunodeficiency virus-infected adolescents in Zimbabwe: a strong indicator of underlying HIV infection.津巴布韦感染人类免疫缺陷病毒的青少年中的皮肤疾病:潜在 HIV 感染的强烈指标。
Pediatr Infect Dis J. 2010 Apr;29(4):346-51. doi: 10.1097/INF.0b013e3181c15da4.
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Determinants of transitions to first sexual intercourse, marriage and pregnancy among female adolescents: evidence from South Nyanza, Kenya.肯尼亚南尼安萨地区女性青少年首次性行为、婚姻和怀孕转变的决定因素:证据
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Education and vulnerability: the role of schools in protecting young women and girls from HIV in southern Africa.教育与脆弱性:南部非洲学校在保护年轻女性和女孩免受艾滋病毒感染方面的作用。
AIDS. 2008 Dec;22 Suppl 4:S41-56. doi: 10.1097/01.aids.0000341776.71253.04.
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Structural approaches to HIV prevention.艾滋病病毒预防的结构性方法。
Lancet. 2008 Aug 30;372(9640):764-75. doi: 10.1016/S0140-6736(08)60887-9. Epub 2008 Aug 5.
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The gradient in sub-Saharan Africa: socioeconomic status and HIV/AIDS.撒哈拉以南非洲地区的梯度差异:社会经济地位与艾滋病毒/艾滋病
Demography. 2008 May;45(2):303-22. doi: 10.1353/dem.0.0006.
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Effectiveness of web-based education on Kenyan and Brazilian adolescents' knowledge about HIV/AIDS, abortion law, and emergency contraception: findings from TeenWeb.基于网络的教育对肯尼亚和巴西青少年关于艾滋病毒/艾滋病、堕胎法及紧急避孕知识的效果:来自青少年网络的研究结果
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From affected to infected? Orphanhood and HIV risk among female adolescents in urban Zimbabwe.从受影响到被感染?津巴布韦城市地区女性青少年中的孤儿身份与感染艾滋病毒的风险
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支持青少年孤儿女童接受教育以预防艾滋病毒风险:来自津巴布韦一项随机对照试验的证据。

Supporting adolescent orphan girls to stay in school as HIV risk prevention: evidence from a randomized controlled trial in Zimbabwe.

机构信息

Pacific Institute for Research and Evaluation, 1516 E Franklin St, Suite 200, Chapel Hill, NC 27514, USA.

出版信息

Am J Public Health. 2011 Jun;101(6):1082-8. doi: 10.2105/AJPH.2010.300042. Epub 2011 Apr 14.

DOI:10.2105/AJPH.2010.300042
PMID:21493943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3093274/
Abstract

OBJECTIVES

Using a randomized controlled trial in rural eastern Zimbabwe, we tested whether comprehensive support to keep orphan adolescent girls in school could reduce HIV risk.

METHODS

All orphan girls in grade 6 in 25 primary schools were invited to participate in the study in fall 2007 (n = 329). Primary schools were randomized to condition. All primary schools received a universal daily feeding program; intervention participants received fees, uniforms, and a school-based helper to monitor attendance and resolve problems. We conducted annual surveys and collected additional information on school dropout, marriage, and pregnancy rates. We analyzed data using generalized estimating equations over 3 time points, controlling for school and age at baseline.

RESULTS

The intervention reduced school dropout by 82% and marriage by 63% after 2 years. Compared with control participants, the intervention group reported greater school bonding, better future expectations, more equitable gender attitudes, and more concerns about the consequences of sex.

CONCLUSIONS

We found promising evidence that comprehensive school support may reduce HIV risk for orphan girls. Further study, including assessment of dose response, cost benefit, and HIV and herpes simplex virus 2 biomarker measurement, is warranted.

摘要

目的

我们在津巴布韦东部农村地区开展了一项随机对照试验,旨在检验全面支持使孤儿少女继续接受教育能否降低艾滋病毒感染风险。

方法

2007 年秋季,邀请 25 所小学六年级的所有孤儿少女参加研究(n=329)。对小学进行随机分组。所有小学都实施普及性每日供餐方案;干预组的参与者还获得学费、校服和一名学校助手,以监督出勤率并解决问题。我们每年开展调查,并收集辍学率、结婚率和怀孕率的额外信息。我们采用广义估计方程,在 3 个时间点进行分析,在校和入学年龄方面进行了控制。

结果

2 年后,干预减少了 82%的辍学和 63%的早婚。与对照组相比,干预组的学校归属感更强,对未来的期望更高,性别态度更加平等,对性行为后果的担忧也更多。

结论

我们发现有希望的证据表明,全面的学校支持可能降低孤儿少女的艾滋病毒感染风险。需要进一步研究,包括评估剂量反应、成本效益以及艾滋病毒和单纯疱疹病毒 2 生物标志物的测量。