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在机械肺模型上使用 HFPV 进行呼吸力学的体外测量。

In vitro measurements of respiratory mechanics during HFPV using a mechanical lung model.

机构信息

Department of Industrial Engineering and Information Technology, University of Trieste, Trieste, Italy.

出版信息

Physiol Meas. 2011 Jun;32(6):637-48. doi: 10.1088/0967-3334/32/6/002. Epub 2011 Apr 15.

DOI:10.1088/0967-3334/32/6/002
PMID:21493980
Abstract

High-frequency percussive ventilation (HFPV) may be defined as flow-regulated time-cycled ventilation that creates controlled pressure and delivers a series of high-frequency subtidal volumes in combination with low-frequency breathing cycles. In recent years, the usefulness of HFPV has been clinically assessed as an alternative to conventional mechanical ventilation. In the clinical practice, HFPV is not an intuitive ventilatory modality and the absence of real-time delivered volume monitoring produces disaffection among the physicians. For this purpose, it would be useful to develop a monitor able to realize a complete online characterization of high-frequency percussive ventilators and to identify the best combination of their parameters according to the specific pathological situation. This paper describes an innovative acquisition and elaboration system based on the use of new generation pressure transducers presenting high sensitivity and fast response. Such a system is compact and inexpensive, and it allows the user to carry out a more correct online characterization of high-frequency percussive ventilators. This output allowed best real-time ventilatory setting, minimizing the potential baro-volutrauma hazard.

摘要

高频脉冲通气(HFPV)可定义为流量调节的时间循环通气,它产生受控压力并结合低频呼吸周期输送一系列高频亚潮气量。近年来,HFPV 的有用性已在临床评估中被视为传统机械通气的替代方法。在临床实践中,HFPV 不是一种直观的通气方式,缺乏实时输送容量监测会导致医生不满。为此,开发一种能够实现高频脉冲通气器的完整在线特性描述并根据特定病理情况确定其参数最佳组合的监视器将是有用的。本文描述了一种基于使用新一代具有高灵敏度和快速响应的压力传感器的创新采集和处理系统。该系统紧凑且价格低廉,允许用户对高频脉冲通气器进行更正确的在线特性描述。这种输出允许最佳实时通气设置,最大限度地降低潜在的压力-容积伤危险。

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