Yeo Sang Seok, Kim Seong Ho, Ahn Young Hwan, Son Su Min, Jang Sung Ho
Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.
Stereotact Funct Neurosurg. 2011;89(3):152-6. doi: 10.1159/000324890. Epub 2011 Apr 14.
We investigated the anatomical location of the pedunculopontine nucleus (PPN) in the human brain using diffusion tensor imaging. Forty normal healthy subjects were recruited. To confirm the boundary of the PPN, we analyzed the superior cerebellar peduncle and medial lemniscus using DTI-Studio software. We identified the PPN on red green blue (RGB) images, and defined four points of the PPN and four boundaries of the midbrain: point a - the most anterior point, point b - the most posterior point, point c - the most medial point, point d - the most lateral point; anterior boundary - the line of the most posterior point of the interpeduncular fossa, posterior boundary - the line of the upper part of the inferior colliculus, lateral boundary - the line of the most lateral point of the midbrain, medial boundary - the line of the midline of the midbrain. Points a and b were located at an average of 20.19 and 30.52% from the anterior boundary, respectively. By contrast, points c and d were located at an average of 22.50 and 41.65% from the medial boundary, respectively. We believe that the methodology and data of this study would be helpful in research and procedures on the PPN.
我们使用扩散张量成像技术研究了人脑脚桥核（PPN）的解剖位置。招募了40名正常健康受试者。为了确定PPN的边界，我们使用DTI-Studio软件分析了上小脑脚和内侧丘系。我们在红绿色蓝（RGB）图像上识别出PPN，并定义了PPN的四个点和中脑的四个边界：点a - 最前点，点b - 最后点，点c - 最内侧点，点d - 最外侧点；前边界 - 脚间窝最后点的连线，后边界 - 下丘上部的连线，外侧边界 - 中脑最外侧点的连线，内侧边界 - 中脑中线的连线。点a和点b分别平均位于距前边界20.19%和30.52%处。相比之下，点c和点d分别平均位于距内侧边界22.50%和41.65%处。我们认为本研究的方法和数据将有助于PPN的研究和手术操作。
