[米屈膦酸二钠用于支气管肺部疾病患者的临床免疫学方面]
[Clinico-immunologic aspects of using mildronate in patients with bronchopulmonary diseases].
作者信息
Orlov V A, Sokolova V I, Zamotaev I P, Elagina L V, Zavolovskaia L I
出版信息
Antibiot Khimioter. 1990 Jul;35(7):47-50.
PMID:2149494
Abstract
The immunity status of 35 patients with chronic bronchitis and infectious and allergic bronchial asthma was studied. Defects in the humoral immunity were revealed. To correct the immunity status, all the patients were treated with mildronate. The immunomodulatory effect of mildronate was found in all the groups of the patients. Mildronate was shown to increase the activity of a secondary immune response and the bronchial potency in the persons with infectious and allergic asthma.
摘要
对35例慢性支气管炎患者以及感染性和过敏性支气管哮喘患者的免疫状态进行了研究。发现存在体液免疫缺陷。为纠正免疫状态，所有患者均接受了米屈膦酸盐治疗。在所有患者组中均发现了米屈膦酸盐的免疫调节作用。结果显示，米屈膦酸盐可增强感染性和过敏性哮喘患者的二次免疫反应活性及支气管效能。
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