• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[基于卡尔梅克自治州尸检数据的儿童艾滋病情况]

[AIDS in children based on autopsy data from the Kalmyk ASSR].

作者信息

Vasil'eva G G, Tsinzerling A V, Kozhemiakin L A, Bondarenko I G

出版信息

Arkh Patol. 1990;52(7):20-6.

PMID:2149495
Abstract

6 cases of HIV infection were revealed by enzyme immunoassay and immunoblotting among 144 children who had died in Elista. Another 5 children might have had HIV-infection but laboratory analyses either were lacking or gave doubtful results. Laboratory results were negative in 133 children. Similar severe changes of the lymphoid system typical for immunodeficiency were found in all children. These changes in HIV infection were characterized by lymphogenic generalized RNA infection. Complications (secondary diseases) in the form of DNA-virus infections (cytomegalia and herpes simplex), pneumocystosis and other viral and bacterial processes were observed in children of all groups. The disease was found mainly in Kalmyks. Blood examination of healthy Kalmyks revealed some differences in the form of significant decrease of the lysosomal cationic proteins content and the peroxydase activity of neutrophil leucocytes as compared to the same indexes obtained in Leningrad. There was also a tendency to the decrease of T-lymphocyte content. The children dying from immunodeficiencies lived mainly along the litoral of an ancient sea.

摘要

在埃利斯塔死亡的144名儿童中,通过酶免疫测定法和免疫印迹法发现6例感染了艾滋病毒。另外5名儿童可能感染了艾滋病毒,但缺乏实验室分析或结果存疑。133名儿童的实验室检查结果为阴性。在所有儿童中均发现了免疫缺陷典型的淋巴系统类似严重变化。这些艾滋病毒感染的变化特征为淋巴源性全身性RNA感染。在所有组的儿童中均观察到以DNA病毒感染(巨细胞病毒和单纯疱疹病毒)、肺孢子菌病以及其他病毒和细菌感染为形式的并发症(继发性疾病)。该疾病主要在卡尔梅克人当中发现。与列宁格勒的健康卡尔梅克人的相同指标相比,对健康卡尔梅克人的血液检查显示,溶酶体阳离子蛋白含量和中性粒细胞过氧化物酶活性显著降低。T淋巴细胞含量也有下降趋势。死于免疫缺陷的儿童主要居住在古代海洋的沿岸地区。

相似文献

1
[AIDS in children based on autopsy data from the Kalmyk ASSR].[基于卡尔梅克自治州尸检数据的儿童艾滋病情况]
Arkh Patol. 1990;52(7):20-6.
2
[Clinical manifestations of HIV infection in children].
Sov Med. 1991(9):79-81.
3
Molecular epidemiology of HIV-1 in the former Soviet Union: analysis of env V3 sequences and their correlation with epidemiologic data.前苏联地区人类免疫缺陷病毒1型的分子流行病学:env V3序列分析及其与流行病学数据的相关性
AIDS. 1994 May;8(5):619-24.
4
[Infection by the human immunodeficiency virus (HIV) in French Guyana. Dermato-venereologic problems].[法属圭亚那的人类免疫缺陷病毒(HIV)感染。皮肤性病问题]
Med Trop (Mars). 1989 Jan-Mar;49(1):21-8.
5
T-lymphocytopaenia, opportunistic infections and pathological findings in Ghanaian AIDS patients and their sexual partners.加纳艾滋病患者及其性伴侣的T淋巴细胞减少、机会性感染和病理检查结果
East Afr Med J. 1997 Dec;74(12):784-91.
6
[The pathological anatomy of HIV infection based on the data from serologically verified cases].[基于血清学确诊病例数据的HIV感染病理解剖学]
Arkh Patol. 1990;52(7):9-16.
7
[Pathology of the internal organs and central nervous system in acquired immunodeficiency syndrome (with special reference to opportunistic infections)].获得性免疫缺陷综合征的内脏器官与中枢神经系统病理学(特别提及机会性感染)
Pathologica. 1990 Jan-Feb;82(1077):41-61.
8
[The morphopathological aspects at autopsy of HIV infection in children].[儿童艾滋病病毒感染尸检的形态病理学特征]
Rev Med Chir Soc Med Nat Iasi. 1997 Jan-Jun;101(1-2):147-52.
9
[AIDS and pediatric HIV infection: the problem of the infected mother and her newborn].[艾滋病与儿童HIV感染:感染母亲及其新生儿的问题]
Rev Latinoam Psicol. 1992;24(1-2):157-67.
10
[Neuropathology of the acquired immunodeficiency syndrome].[获得性免疫缺陷综合征的神经病理学]
Pathologica. 1989 Sep-Oct;81(1075):481-98.