Avtsyn A P, Parkhomenko Iu G, Zhavoronkov A A, Pokrovskiĭ V V, Kelli E I
Arkh Patol. 1990;52(7):9-16.
Pathology of 4 cases of serologically verified HIV infection is described. In 3 cases the disease developed against the background of previous pathologic processes that in one way or another influenced the pathologic picture. Only general characteristics of the HIV pathology are given in this report obtained by routine methods. Detailed investigation of changes in different organs and systems will be continued. Morphological signs of the immunodeficiency manifesting mainly in more or less atrophy of lymphoid tissue were found in all cases examined. Though features specific for HIV infection are not established in the literature, the complex of the above changes allows one to suspect HIV infection and in case of serologic confirmation to formulate a pathologic diagnosis. The 4th case can be regarded as an earlier stage of HIV infection as well as an example of a therapeutically produced pathomorphosis.
本文描述了4例血清学确诊的HIV感染病例的病理学情况。其中3例疾病是在先前病理过程的背景下发生的，这些病理过程以某种方式影响了病理表现。本报告仅给出了通过常规方法获得的HIV病理学的一般特征。对不同器官和系统变化的详细研究将继续进行。在所有检查病例中均发现了免疫缺陷的形态学迹象，主要表现为或多或少的淋巴组织萎缩。尽管文献中尚未确立HIV感染的特异性特征，但上述变化的综合情况使人怀疑HIV感染，血清学确诊后即可做出病理诊断。第4例可视为HIV感染的早期阶段，也是治疗引起的病理形态改变的一个例子。
