Ciortescu Irina, Stanciu C
Institutul de Gastroenterologie si Hepatologie Iaşi, Facultatea de Medicină, Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2009 Apr-Jun;113(2):330-8.
Gastroparesis is a disorder characterized by a delay in gastric emptying of a meal in the absence of a mechanical gastric outlet obstruction. Diagnosis of gastroparesis is based on the presence of symptoms ( nausea, vomiting, postprandial abdominal fullness), excluded mechanical obstruction (endoscopy) and on objectively determined delay in gastric emptying. Gastric emptying can be assessed by scintigraphy and stable isotope breath tests. The true prevalence of gastroparesis is unknown. The aetiology of gastroparesis is diverse. In approximately one third of cases, gastroparesis is related to the presence of diabetes mellitus; one third of case is of unknown cause (idiopathic). Mild disease will respond to dietary and life style measures and prokinetics (domperidone, metoclopramide, erytromicyne). Severe disease can benefit from intrapyloric botulinum toxin injection, gastric pacing or more radical surgical interventions (partial or total gastrectomy).
胃轻瘫是一种在没有机械性胃出口梗阻的情况下，以进餐时胃排空延迟为特征的病症。胃轻瘫的诊断基于症状（恶心、呕吐、餐后腹部饱胀）的存在、排除机械性梗阻（内镜检查）以及客观确定的胃排空延迟。胃排空可通过闪烁扫描法和稳定同位素呼气试验进行评估。胃轻瘫的真实患病率尚不清楚。胃轻瘫的病因多种多样。在大约三分之一的病例中，胃轻瘫与糖尿病的存在有关；三分之一的病例病因不明（特发性）。轻度疾病对饮食和生活方式措施以及促动力药（多潘立酮、甲氧氯普胺、红霉素）有反应。严重疾病可受益于幽门内注射肉毒杆菌毒素、胃起搏或更激进的手术干预（部分或全胃切除术）。
